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Introduction: Twin pregnancy through assisted reproduction techniques is increasing, as are the associated complications.

Objective: Compare maternal and perinatal complications associated with spontaneous twin pregnancy and through assisted reproduction techniques (ART).

Material And Methods: Retrospective comparative and controlled study.

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FRAX, a risk calculator that provides individualized 10-year probabilities of hip and major osteoporotic fracture, has been widely used for fracture risk assessment since its launch in 2008. It is now incorporated into very many guidelines worldwide to inform osteoporosis management. In this review, we explore the development of FRAX and how it enhances fracture risk prediction as compared to use of bone mineral density alone, as well as approaches to utilizing FRAX in determining intervention and assessment thresholds.

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Increasing incidence of is driven by people living with HIV and PrEP users.

Int J STD AIDS

January 2025

Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Background: (MG) is responsible for non-gonococcal urethritis. Our aim is to describe MG positivity rate and incidence in specific populations.

Methods: Retrospective, surveillance study included all samples collected from 2018 to 2022.

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Distinct genetic risk loci between biopsy-proven renal and non-renal lupus: a 10-year longitudinal cohort.

Rheumatology (Oxford)

January 2025

Division of Rheumatology & Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong.

Objective: Systemic lupus erythematosus (SLE) is a heterogeneous disease which manifests as different subphenotypes. Distinct subphenotypes, such as lupus nephritis (LN), have been associated with increased genetic risk, but prior studies have been limited by cross-sectional and imprecisely subphenotyped cohorts. This study investigated the genetic basis for LN using a longitudinal cohort of distinctly subphenotyped patients.

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Background: Per- and polyfluoroalkyl substances (PFAS) comprise thousands of fluorinated chemicals. They are of growing concern because many PFAS compounds are persistent and toxic. Food contact materials (FCM) containing PFAS pose multiple exposure pathways to humans, prompting twelve states to enact laws banning FCM with PFAS levels exceeding 100 ppm of TOF.

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