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Biomimetics (Basel)
January 2025
Bioengineering Laboratory, Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803, USA.
The development of biocompatible hydrogels for 3D bioprinting is essential for creating functional tissue models and advancing preclinical drug testing. This study investigates the formulation, printability, mechanical properties, and biocompatibility of a novel Alg-Gel hydrogel blend (alginate and gelatin) for use in extrusion-based 3D bioprinting. A range of hydrogel compositions were evaluated for their rheological behavior, including shear-thinning properties, storage modulus, and compressive modulus, which are crucial for maintaining structural integrity during printing and supporting cell viability.
View Article and Find Full Text PDFBiomimetics (Basel)
December 2024
Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, Changchun 130022, China.
Slender tubes are in high demand owing to their lightweight and outstanding energy absorption. However, conventional slender tubes are prone to catastrophic failures such as Euler's buckling under axial load. Interestingly, growing bamboos overcome this similar dilemma via a unique tapered intine in the internodes, which endows them with excellent energy absorption.
View Article and Find Full Text PDFBioengineering (Basel)
December 2024
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94115, USA.
In exploring adjuvant therapies for head and neck cancer, hyperthermia (40-45 °C) has shown efficacy in enhancing chemotherapy and radiation, as well as the delivery of liposomal drugs. Current hyperthermia treatments, however, struggle to reach large deep tumors uniformly and non-invasively. This study investigates the feasibility of delivering targeted uniform hyperthermia deep into the tissue using a non-invasive ultrasound spherical random phased array transducer.
View Article and Find Full Text PDFJ Endovasc Ther
January 2025
Department of Vascular Surgery, The Chaim Sheba Medical Center, Tel HaShomer, Ramat Gan, Israel.
Purpose: To report a case series on using a novel semi-branch feature in custom-made stent-grafts in the endovascular treatment of complex aortic aneurysms and summarize the contemporary usage of this technology.
Case Series: Four patients underwent endovascular aortic aneurysm repair (EVAR) with a custom-made semi-branch stent-graft (Semi-Branch Endovascular Aortic Aneurysm Repair [SBEVAR]). Two male patients, 75- and 76-year-old, were treated due to failed EVAR with late-type Ia endoleak, and the other two, 80- and 55-year-old male patients, due to a juxta-renal aortic abdominal aneurysm (JRAAA).
Ultrasonics
January 2025
State Key Laboratory of Intelligent Manufacturing Equipment and Technology, School of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, China.
Steel precision matching parts are widely used in aerospace and automobiles. In order to ensure the stability of the system, the matching parts' mating surfaces, such as inner holes and outer shafts, are required to achieve nano-surface roughness and submicron-shape accuracy. Diamond-cutting technology is generally used for ultra-precision machining processes.
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