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A Simple Sensitivity Analysis Method for Unmeasured Confounders via Linear Programming With Estimating Equation Constraints.
Stat Med
February 2025
Department of Biomedical Statistics, Graduate School of Medicine, Osaka University, Osaka, Japan.
In estimating the average treatment effect in observational studies, the influence of confounders should be appropriately addressed. To this end, the propensity score is widely used. If the propensity scores are known for all the subjects, bias due to confounders can be adjusted by using the inverse probability weighting (IPW) by the propensity score.
View Article and Find Full Text PDFBetaine-homocysteine methyltransferase attenuates liver ischemia-reperfusion injury by targeting TAK1.
FASEB J
January 2025
Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liver ischemia-reperfusion (IR) injury is a common complication following liver surgery, significantly impacting the prognosis of liver transplantation and other liver surgeries. Betaine-homocysteine methyltransferase (BHMT), a crucial enzyme in the methionine cycle, has been previously confirmed the pivotal role in hepatocellular carcinoma, and it has also been demonstrated that BHMT inhibits inflammation, apoptosis, but its role in liver IR injury remains unknow. Following I/R injury, we found that BHMT expression was significantly upregulated in human liver transplant specimens, mice and hepatocytes.
View Article and Find Full Text PDFDesign and Validation of a Biomimetic Leg-Claw Mechanism Capable of Perching and Grasping for Multirotor Drones.
Biomimetics (Basel)
December 2024
School of Mechanical Engineering, University of Science and Technology Beijing, Beijing 100083, China.
Multirotor drones are widely used in fields such as environmental monitoring, agricultural inspection, and package delivery, but they still face numerous challenges in durability and aerial operation capabilities. To address these issues, this paper presents a biomimetic leg-claw mechanism (LCM) inspired by the biomechanics of birds. The claw of the LCM adopts a bistable gripper design that can rapidly close through external impact or actively close via the coordination of internal mechanisms.
View Article and Find Full Text PDFAnalysis of Connectivity in Electromyography Signals to Examine Neural Correlations in the Activation of Lower Leg Muscles for Postural Stability: A Pilot Study.
Bioengineering (Basel)
January 2025
School of Engineering, Grand Valley State University, Grand Rapids, MI 49504, USA.
In quiet standing, the central nervous system implements a pre-programmed ankle strategy of postural control to maintain upright balance and stability. This strategy comprises a synchronized common neural drive delivered to synergistically grouped muscles. This study evaluated connectivity between EMG signals of the unilateral and bilateral homologous muscle pairs of the lower legs during various standing balance conditions using magnitude-squared coherence (MSC).
View Article and Find Full Text PDFSurgical outcomes of subclavian steal syndrome combined with carotid artery stenosis: A single-center retrospective observational study.
Sci Prog
January 2025
Department of Vascular Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, China.
Objective: To explore the prevalence and risk factors of carotid artery (CA) stenosis among subclavian steal syndrome (SSS) patients and to record their prognoses.
Methods: This observational study was retrospective. From January 2015 to October 2022, 169 patients were diagnosed with SSS.
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