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Assessing Preferences of Patients with Chronic Spontaneous Urticaria for Injectable Treatment Profiles.
Patient
January 2025
Division of Rheumatology, Allergy and Immunology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Background: In the context of injectable biologic products approved or in development for chronic spontaneous urticaria (CSU), it is important to capture which treatment attributes matter most to patient and what trade-offs patients are willing to make.
Objectives: The CHOICE-CSU study aimed to quantify patient preferences toward injectable treatment attributes among patients with CSU, inadequately controlled by H1-antihistamines.
Methods: This was a two-phase cross-sectional patient preference study in adult patients with a diagnosis of CSU, inadequately controlled by H1-antihistamines.
Achievement emotions in kindergarten: the association of solution accuracy with discrete joy, sadness, and surprise.
Front Psychol
January 2025
School of Education and Human Development, Center for the Advanced Study of Teaching and Learning, University of Virginia, Charlottesville, VA, United States.
Children experience a variety of emotions in achievement settings. Yet, mathematics-related emotions other than anxiety are understudied, especially for young children entering primary school. The current study reports the prevalence and intensity of six basic, discrete achievement emotions (joy/happiness, sadness, surprise, anger, fear, and disgust) expressed on the faces of 15 kindergarten-aged children as they solved increasingly complex arithmetic story problems in a 3-month teaching experiment.
View Article and Find Full Text PDFSpatial, temporal, and spatiotemporal cluster detection of malaria incidence in Southwest Ethiopia.
Front Public Health
January 2025
Department of Environmental and Occupational Health and Safety, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Background: Malaria is a major global health hazard, particularly in developing countries such as Ethiopia, where it contributes to high morbidity and mortality rates. According to reports from the South Omo Zone Health Bureau, despite various interventions such as insecticide-treated bed nets and indoor residual spraying, the incidence of malaria has increased in recent years. Therefore, this study aimed to assess the spatial, temporal, and spatiotemporal variation in malaria incidence in the South Omo Zone, Southwest Ethiopia.
View Article and Find Full Text PDFSuperstrong Lightweight Aerogel with Supercontinuous Layer by Surface Reaction.
Adv Mater
January 2025
Key Laboratory of Precision and Intelligent Chemistry, CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, National Synchrotron Radiation Laboratory, Center for Micro and Nanoscale Research and Fabrication, Institute of Advanced Technology, University of Science and Technology of China, Hefei, 230026, P. R. China.
Breaking the thermal, mechanical and lightweight performance limit of aerogels has pivotal significance on thermal protection, new energy utilization, high-temperature catalysis, structural engineering, and physics, but is severely limited by the serious discrete characteristics between grain boundary and nano-units interfaces. Herein, a thermodynamically driven surface reaction and confined crystallization process is reported to synthesize a centimeter-scale supercontinuous ZrO nanolayer on ZrO-SiO fiber aerogel surface, which significantly improved its thermal and mechanical properties with density almost unchanged (≈26 mg cm). Systematic structure analysis confirms that the supercontinuous layer achieves a close connection between grains and fibers through Zr─O─Si bonds.
View Article and Find Full Text PDFOptimized design and experimental analysis of the vertical mixing plow for enhancing planosol improvement machine.
Sci Rep
January 2025
Intelligent Agricultural Machinery Equipment Engineering Laboratory, Harbin Cambridge University, Harbin, Heilongjiang, China.
Improved soil fertility to sustain crop productivity is important to enhance agroecosystem services. To address the low nutrient content, subsoil compaction, and poor root penetration in Planosol, a new machine was designed to improve these conditions. This machine integrates subsoil mixing and fertilizer application.
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