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Injury can cause differentiated cells to undergo massive reprogramming to become proliferative to repair tissue via a cellular program called paligenosis. Gastric digestive-enzyme-secreting chief cells use paligenosis to reprogram into progenitor-like Spasmolytic-Polypeptide Expressing Metaplasia (SPEM) cells. Stage 1 of paligenosis is to downscale mature cell architecture via a process involving lysosomes.
View Article and Find Full Text PDFTuneable Cell-Laden Double-Emulsion Droplets for Enhanced Signal Detection.
Anal Chem
January 2023
School of Engineering, Macquarie University, Sydney, New South Wales 2109, Australia.
Water-in-oil-in-water (w/o/w) or double-emulsion (DE) droplets have been widely used for cellular assays at a single-cell level because of their stability and biocompatibility. The oil shell of w/o/w droplets plays the role of a semipermeable membrane that allows substances with low molecular weight (e.g.
View Article and Find Full Text PDFMild hydrogen peroxide interceded bacterial disintegration of waste activated sludge for efficient biomethane production.
Sci Total Environ
April 2022
Department of Physics, Anna University Regional Campus, Tirunelveli, Tamil Nadu 627007, India. Electronic address:
Regardless of the issue of sludge management all over the world, the role of phase separated pretreatment prior to anaerobic digestion are more promising in terms of energy efficient biomethane production. However, the effect of phase separated pretreatment (dissociation of extracellular polymeric substances (EPS) followed by biological pretreatment in a two-step process) must be sensibly evaluated from various perceptions to consolidate its effectiveness in sludge management and bioenergy recovery. In this study, mild hydrogen peroxide induced bacterial pretreatment (HO-BP) was employed as phase separated pretreatment to investigate the effectiveness of EPS dissociation prior to biological pretreatment on sludge solubilization and biomethanation.
View Article and Find Full Text PDFSulfakinin is an important regulator of digestive processes in the migratory locust, Locusta migratoria.
Insect Biochem Mol Biol
June 2015
Molecular Developmental Physiology and Signal Transduction, Department of Biology, KU Leuven, Naamsestraat 59, Leuven, Vlaams-Brabant, Belgium. Electronic address:
Sulfakinin (SK) is a sulfated insect neuropeptide that is best known for its function as a satiety factor. It displays structural and functional similarities with the vertebrate peptides gastrin and cholecystokinin. Peptidomic studies in multiple insects, crustaceans and arachnids have revealed the widespread occurrence of SK in the arthropod phylum.
View Article and Find Full Text PDFInsights into the Nanobiology of Growth Hormone Secretion.
Discoveries (Craiova)
September 2014
Department of Animal Science, College of Agriculture and Life Sciences and Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011-3150 USA.
The fact that partially empty vesicles are generated following cell secretion suggested that secretory vesicles do not collapse at the cell plasma membrane but, rather, transiently dock and fuse at the plasma membrane to expel a portion of their contents before retracting or undergoing endocytosis into the cell. Such a process has also been referred to in the literature as a "kiss-and-run" mechanism. This mechanism of cell secretion was conclusively demonstrated following the discovery of permanent cup-shaped lipoprotein structures at the cell plasma membrane, called "porosomes", where secretory vesicles transiently dock and fuse to expel intravesicular contents from the cell.
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