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Distraction osteogenesis is a valuable clinical technique used to address length discrepancies in long bone deformities. This procedure involves performing an osteotomy at an appropriate site in the bone and correcting the deformity through an extension system. This research aims to investigate the efficacy of a newly developed device for use in rat tibias and to provide an alternative to existing devices used in animal experiments.

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Objective: To examine the experiences of individuals with acquired brain injury and their partners regarding the effects of social cognition problems on their relationships.

Design: Qualitative interview study.

Setting: Interviews were conducted 1 to 5 years post-injury, either in the participants' home or at a care facility in the Netherlands.

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Toward Automated Simulation Research Workflow through LLM Prompt Engineering Design.

J Chem Inf Model

January 2025

The State Key Laboratory of Molecular Engineering of Polymers, The Research Center of AI for Polymer Science Department of Macromolecular Science, Fudan University, Shanghai 200433, China.

The advent of Large Language Models (LLMs) has created new opportunities for the automation of scientific research spanning both experimental processes and computational simulations. This study explores the feasibility of constructing an autonomous simulation agent (ASA) powered by LLMs through prompt engineering and automated program design to automate the entire simulation research process according to a human-provided research plan. This process includes experimental design, remote upload and simulation execution, data analysis, and report compilation.

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Domestic violence and abuse (DVA) is a global problem that affects approximately one in four women in their lifetime. An area of unexplored research is how women use a range of strategies to honor resistance, manage the risk, avoid abuse, and cope with the pain of DVA. Art-based methodology and interpretative phenomenological analysis approaches were used which determined seven strategies employed by women in order to survive DVA: apparent compliance; maintaining a sense of self; knowing boundaries; keeping hope in sight; imagining freedom; degrees of rebellion; and denial.

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Background: In Nigeria, men constitute over half of the people notified with tuberculosis (TB), experience longer delays before reaching care, and are estimated to account for two thirds of people who miss out on care. The higher TB risk and burden in men has implications for the whole population and reaching them earlier with TB services will reduce onward transmission in households, communities, and workplaces. The absence of a comprehensive guidance and the lack of substantial empirical evidence on TB care approaches that are responsive to the needs of men in Nigeria exacerbates this problem.

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