Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Utilizing metabolomic profiling as a supportive diagnostic tool for radiologically isolated syndrome.
Mult Scler Relat Disord
January 2025
Sancaktepe Prof.Dr.Ilhan Varank State Hospital, Neurology, Turkey.
Background: Radiologically Isolated Syndrome (RIS) characterized by abnormalities on MRI that do not manifest as clinical symptoms of Multiple Sclerosis (MS) but raise suspicion for MS. Considering that RIS often evolves into MS, various diagnostic criteria have been established, and each suggested biomarker warrants thorough consideration and discussion. In this study, metabolomic profiling of body fluids of patients who were being followed up with a pre-diagnosis of RIS or MS and had not yet received any treatment was conducted.
View Article and Find Full Text PDFHypokalemia-Induced Rhabdomyolysis Secondary to Adrenal Adenoma: A Case Report.
Cureus
December 2024
Pulmonary and Critical Care Medicine, Icahn School of Medicine at Mount Sinai/New York City Health + Hospitals - Queens, New York City, USA.
Adrenal adenoma, which leads to increased production of the hormone aldosterone, commonly presents as hypertension and hypokalemia. Rhabdomyolysis as a result of hypokalemia secondary to primary hyperaldosteronism is a rare but important complication with only a few reported cases. Low potassium levels can disrupt the regulation of arteriolar musculature, leading to reduced blood flow to skeletal muscles.
View Article and Find Full Text PDFAssociation between serum albumin levels at admission and clinical outcomes in pediatric intensive care units: a multi-center study.
BMC Pediatr
December 2024
Department of Pediatric Intensive Care, Faculty of Medicine, Cukurova University, Adana, Turkey.
Background: Albumin, a vital component in regulating human blood oncotic pressure, plays an important role in the prediction of prognosis in pediatric patients.Previous research identified significant differences in serum albumin levels of healthy and critically ill children.
Methods: The present study aims to investigate the correlation between albumin levels measured during pediatric intensive care unit(PICU) admission and clinical outcomes.
Resorcimoline as a Novel Therapeutic Agent Attenuates Ischemia-Reperfusion Injury in Hind Extremities.
Ann Vasc Surg
December 2024
Department of Cardiovascular Surgery, Oita University Faculty of Medicine, Oita, Japan.
Background: Acute ischemia in the hind extremities is a dangerous disease that causes irreversible damage. Revascularization procedures are important to prevent muscle damage, but these treatments may induce additional damage, also known as ischemia-reperfusion injury. The role of free radicals as pivotal mediators of ischemia-reperfusion injury remains a prominent hypothesis.
View Article and Find Full Text PDFStructural and Functional Integration of Tissue-Nonspecific Alkaline Phosphatase Within the Alkaline Phosphatase Superfamily: Evolutionary Insights and Functional Implications.
Metabolites
November 2024
Molecular Microbiology and Structural Biochemistry, UMR 5086, CNRS, University Lyon, F-69367 Lyon, France.
Phosphatases are enzymes that catalyze the hydrolysis of phosphate esters. They play critical roles in diverse biological processes such as extracellular nucleotide homeostasis, transport of molecules across membranes, intracellular signaling pathways, or vertebrate mineralization. Among them, tissue-nonspecific alkaline phosphatase (TNAP) is today increasingly studied, due to its ubiquitous expression and its ability to dephosphorylate a very broad range of substrates and participate in several different biological functions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!