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Bispectral Index-Monitored Anesthesia Induction in Older Adults Undergoing Elective Surgery: Comparing Ciprofol and Propofol in a Prospective, Single-Center, Double-Blind, Randomized Controlled Study.
Drug Des Devel Ther
November 2024
Department of Anesthesiology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, People's Republic of China.
Article Synopsis
- Ciprofol is a new sedative anesthetic that shows promise for older adults, particularly in reducing hypotension during anesthesia induction compared to propofol.
- In a study of 117 older adults, ciprofol resulted in a lower incidence of hypotension (26.3%) compared to propofol (48.3%).
- Patients receiving ciprofol also reported less injection pain and maintained stable blood pressure levels while achieving successful anesthesia induction in both groups.
Effect of intravenous palonosetron on hypotension induced by spinal anesthesia for cesarean section: A randomized controlled trial.
PLoS One
June 2024
Department of Anesthesiology and Pain Medicine, College of Medicine, Chung-Ang University, Seoul, South Korea.
Background: The aim of this study was to evaluate the impact of intravenous palonosetron compared to ondansetron on hypotension induced by spinal anesthesia in women undergoing cesarean section.
Methods: Fifty-four women scheduled for elective cesarean section were, randomly allocated to ondansetron group (n = 27) or palonosetron group (n = 27). Ten minutes prior to the administration of spinal anesthesia, participants received an intravenous injection of either ondansetron or palonosetron.
Postspinal Anesthesia Hypotension in Caesarean Delivery: A Narrative Review.
Cureus
April 2024
Anesthesiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Anesthesiologists frequently deal with spinal hypotension when administering spinal anesthesia (SA) for a Caesarean section (C-section). The physiological changes that occur during pregnancy necessitate modifications to anesthesia and analgesia procedures to provide safe and efficient care for the expectant patient. It is believed that giving the patient SA during a C-section will increase their degree of comfort and pain management both during and after the surgical process.
View Article and Find Full Text PDFThe predictive role of carotid artery flow time for anesthesia-induced hypotension in high-risk elderly patients.
J Clin Monit Comput
August 2024
Department of Anesthesiology and Reanimation, Cukurova University, Adana, Turkey.
Hypotension induced by general anesthesia is associated with postoperative complications, increased mortality, and morbidity, particularly elderly patients. The aim of this study was to investigate the effectiveness of corrected carotid artery flow time (FTc) for predicting hypotension following anesthesia induction in patients over 65 years old. After faculty ethical committee approval and written informed consent, 138 patients (65 years and older, ASA physical status I-III) who scheduled for elective surgery were included in this study.
View Article and Find Full Text PDFType 2 Myocardial Infarction Caused by Orthostatic Hypotension With Post-transcatheter Aortic Valve Implantation: A Case Report.
Cureus
February 2024
Community Care, Unnan City Hospital, Unnan, JPN.
This case report delineates the occurrence and management of type 2 myocardial infarction (MI) in an 89-year-old woman following transcatheter aortic valve implantation (TAVI). The patient, with a history of severe aortic stenosis, hypertension, dyslipidemia, and colorectal cancer, presented with nausea and significant hypotension. Initial assessments revealed elevated troponin levels, atrial fibrillation, and ST-segment depression, leading to a diagnosis of type 2 MI.
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