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Structural, physical characteristics and biological activities assessment of scleroglucan from a local strain Athelia rolfsii TEMG.
Int J Biol Macromol
November 2020
Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Div., National Research Centre, Dokki, Cairo, Egypt. Electronic address:
Athelia rolfsii TEMG (MH 236106) an exopolysaccharide (EPS) producing fungal strain was isolated and identified. Extraction, purification, characterization, antimicrobial, antioxidant, antiviral and antitumor activities of the polysaccharide were investigated. It characterized as a homopolysaccharide of glucose with a molecular weight of 345.
View Article and Find Full Text PDFMicrobial production of scleroglucan and downstream processing.
Front Microbiol
November 2015
Laboratorio de Biotecnología Fúngica, Planta Piloto de Procesos Industriales Microbiológicos-CONICET San Miguel de Tucumán, Argentina ; Cátedra de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Catamarca San Fernando del Valle de Catamarca, Argentina.
Synthetic petroleum-based polymers and natural plant polymers have the disadvantage of restricted sources, in addition to the non-biodegradability of the former ones. In contrast, eco-sustainable microbial polysaccharides, of low-cost and standardized production, represent an alternative to address this situation. With a strong global market, they attracted worldwide attention because of their novel and unique physico-chemical properties as well as varied industrial applications, and many of them are promptly becoming economically competitive.
View Article and Find Full Text PDFRole for toll-like receptor 4 in TNF-alpha secretion by murine macrophages in response to polysaccharide Krestin, a Trametes versicolor mushroom extract.
Fitoterapia
October 2010
Bastyr University, Department of Basic Sciences, School of Natural Health Sciences, Kenmore, WA 98028, USA.
Woody fungi and yeast preparations show promise in cancer treatment by activating anti-tumor immune responses. Macrophages (J774A.1) were treated with PSK, Reishi extract, scleroglucan or vehicle control.
View Article and Find Full Text PDFMicrobial polysaccharides and their derivatives as current and prospective pharmaceuticals.
Curr Pharm Des
January 2009
Institute of Environmental Research, Technical University of Dortmund, Otto-Hahn-Str. 6, 44221 Dortmund, Germany.
The ability to produce polysaccharides is widely found among microbial species. The structural diversity of the microbial polysaccharides (MPS) leads to a wide diversity of their applications. This review focuses pharmacological properties of MPS and their derivatives.
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