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Mitral Valve Prolapse Caused by TLL1 Gain-of-Function Mutation.
Can J Cardiol
January 2025
The Morris Kahn Laboratory of Human Genetics, Faculty of Health Sciences and National Institute of Biotechnology in the Negev, Ben Gurion University of the Negev, Be'er Sheva, Israel; Genetics Institute, Soroka University Medical Center, Be'er Sheva, Israel; The Danek Gertner Institute of Human Genetics, Sheba Medical Center, Ramat Gan, Israel. Electronic address:
Background: Mitral valve prolapse (MVP) is a common cardiac valvular anomaly that can be caused by mutations in genes of various biological pathways. Individuals of three generations of a kindred presented with apparently dominant heredity of isolated MVP.
Methods: Clinical evaluation and echocardiography for all complying family members (n=13).
Oxidation state of bioavailable dissolved organic matter influences bacterioplankton respiration and growth efficiency.
Commun Biol
January 2025
Marine Science Institute/Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara, CA, USA.
Oxygen consumption by oceanic microbes can predict respiration (CO production) but requires an assumed respiratory quotient (RQ; ΔO/ΔCO). Measured apparent RQs (ARQs) can be impacted by various processes, including nitrification and changes in dissolved organic matter (DOM) composition, leading to discrepancies between ARQ and actual RQ. In DOM remineralization experiments conducted in the eastern North Atlantic Ocean, ARQs averaged 1.
View Article and Find Full Text PDFAdverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study.
Am J Med Genet C Semin Med Genet
January 2025
Department of Women's and Children's Health, University of Liverpool, Liverpool, UK.
Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular function, and ambulatory blood pressure (BP). Biochemical indicators of cardiovascular risk were also measured.
View Article and Find Full Text PDFLarvicidal activity of methanolic and aqueous extracts of Lavandula dentata and Nerium oleander flowers against the vector of avian malaria Culiseta longiareolata.
Trop Biomed
December 2024
Farhat Abbes University, Department of Biochemistry, Biochemistry Laboratory, Setif, Algeria.
In light of the adverse effects of chemical insecticides on the environment and human health, as well as the development of mosquito resistance to them, this study explores the potential of methanol and aqueous flower extracts from Lavandula dentata and Nerium oleander as bioinsecticides against Culiseta longiareolata mosquitoes. Additionally, it aims to assess the impact of these extracts on enzymatic biomarkers and biochemical composition of fourth instar larvae of Culiseta longiareolata.Qualitative analysis revealed the presence of flavonoids, terpenes, gallic and catechic tannins in both plant extracts.
View Article and Find Full Text PDFDifferential effects of warming on carbon budget, photosynthetic yield and biochemical composition of cold-temperate and Arctic isolates of Laminaria digitata (Phaeophyceae).
J Plant Physiol
January 2025
Department of Ecology, Faculty of Sciences, University of Málaga, Málaga, Spain.
Cold-temperate and Arctic hard bottom coastal ecosystems are dominated by kelp forests, which have a high biomass production and provide important ecosystem services, but are subject to change due to ocean warming. However, the photophysiological response to increasing temperature of ecologically relevant species, such as Laminaria digitata, might depend on the local thermal environment where the population has developed. Therefore, the effects of temperature on growth rate, biochemical composition, maximum quantum yield, photosynthetic quotient and carbon budget of young cultured sporophytes of Laminaria digitata from the Arctic at Spitsbergen (SPT; cultured at 4, 10 and 16 °C) and from the cold-temperate North Sea island of Helgoland (HLG; cultured at 10, 16 and 22 °C) were comparatively analyzed.
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