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Pheochromocytoma (PHEO) currently is considered to be malignant due to metastatic potential. One of the most common familial forms of PHEO is multiple endocrine neoplasia syndrome (MEN) type 2. The penetrance of PHEO in MEN2 syndrome is up to 50% of cases.
View Article and Find Full Text PDFProposal of staging system and treatment guideline for diagnostically challenging primary intra-osseous carcinoma: A retrospective single-center case series and literature review.
J Stomatol Oral Maxillofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul National University Dental Hospital, Seoul, 03080, South Korea; Department of One-Stop Specialty Center, Seoul National University Dental Hospital, Seoul, South Korea. Electronic address:
The objective of this retrospective study is to examine the clinical, imaging and pathologic features of 10 patients diagnosed with 'primary intraosseous carcinoma (PIOC)' at a single institution and to identify factors affecting the prognosis of PIOC patients. By proposing a new staging system based on tumor size, cortical bone deformation, neck metastasis and histologic grade, the study aims to address the lack of a distinct staging system, which has led to the mixed use of oral squamous cell carcinoma classification. Furthermore, the study intends to propose a treatment guideline based on the newly proposed staging system.
View Article and Find Full Text PDF[Is the use of total vertebrectomy justified for single vertebral metastases? Presentation of one clinical case and review of the literature].
Acta Ortop Mex
January 2025
Servicio de Cirugía Ortopédica y Traumatológica, Hospital Universitari d'Igualada. Igualada, Barcelona, España.
Introduction: the indication for total vertebrectomy in single vertebral metastases is increasingly questioned, especially in metastases with unknown primary tumour.
Material And Methods: in this article we describe a case of vertebral metastasis of unknown primary tumour treated by total vertebrectomy, and a review of the literature.
Results: in those patients with a good general condition, single vertebral metastases and no involvement of internal organs, as in our case, curative surgical treatment can be considered with total vertebrectomy being the treatment of choice in lesions that only affect the body of the vertebra.
High PSMA Avidity, Yet Still Benign: The Importance of CT Morphology for Diagnosing Fibrous Dysplasia on PSMA-Targeted PET/CT.
Clin Nucl Med
January 2025
From the Molecular Imaging and Therapy, Hoag Family Cancer Institute, Irvine, CA.
A 64-year-old man with newly diagnosed prostate cancer underwent 18F-Piflufolastat PET/CT. Radiotracer avidity localized to the primary prostate malignancy and to a left rib (SUVmax, 9.0).
View Article and Find Full Text PDFGastric carcinoma leading to metastatic spinal cord compression.
J Pak Med Assoc
January 2025
Department of Oncology, Ziauddin University, Karachi, Pakistan.
Gastric cancer is described as a malignancy occurring in the region between the gastroesophageal junction and the pylorus. According to the histology, majority of gastric cancers are classified as adenocarcinomas. The prevalence of bone metastasis in the general population is 2-3%.
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