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Tooth loss, periodontal infection and their relationship to cognitive impairment and other dementias: A review.
Neuro Endocrinol Lett
December 2024
Private Practice, Zubná Pohotovosť, s.r.o. Bratislava, Krížna 44, Slovakia.
Our review study addresses the issue of tooth loss, which is caused by loss of masticatory function and its impact on cognitive functions, dementia, and Alzheimer's disease. Numerous studies have confirmed a positive correlation between premature tooth loss, reduction in masticatory function and significant cognitive decline observed through learning disabilities, including overcoming ordinary life problems to early and advanced forms of dementia. Reduced numbers of teeth in the main food processing area, i.
View Article and Find Full Text PDFInverse association between the molecular spreading of IgE to grass pollen and the IgE response to among children with seasonal allergic rhinitis.
World Allergy Organ J
October 2024
Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Augustenburger Platz 1, 13353 Berlin, Germany.
Article Synopsis
- Seasonal allergic rhinoconjunctivitis (SAR) is a common problem for many people, especially in Western countries, and researchers studied its connection to different types of pollen and non-pollen allergens.
- The study looked at the IgE antibodies in patients' blood to see how these antibodies reacted to both grass pollen and a specific dust mite allergen.
- The results showed that having more IgE responses to dust mite proteins was linked to having higher overall IgE levels for pollens, but lower levels for the dust mite allergen itself.
Clenching the Strings of Bruxism Etiopathogenesis: Association Analyses on Genetics and Environmental Risk Factors in a Deeply Characterized Italian Cohort.
Biomedicines
January 2024
Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Via dell'Istria 65, 34137 Trieste, Italy.
Bruxism is a worldwide oral health problem. Although there is a consensus about its multifactorial nature, its precise etiopathogenetic mechanisms are unclear. This study, taking advantage of a deeply characterized cohort of 769 individuals (aged 6-89 years) coming from Northern Italy's genetically isolated populations, aims to epidemiologically describe environmental risk factors for bruxism development and identify genes potentially involved through a Genome-Wide Association Study (GWAS) approach.
View Article and Find Full Text PDFAutoimmunity and Autoinflammation: Relapsing Polychondritis and VEXAS Syndrome Challenge.
Int J Mol Sci
February 2024
Discipline of Rheumatology, Medical Department II, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Relapsing polychondritis is a chronic autoimmune inflammatory condition characterized by recurrent episodes of inflammation at the level of cartilaginous structures and tissues rich in proteoglycans. The pathogenesis of the disease is complex and still incompletely elucidated. The data support the important role of a particular genetic predisposition, with HLA-DR4 being considered an allele that confers a major risk of disease occurrence.
View Article and Find Full Text PDFBackground: Back pain is currently one of the most urgent problems within pain syndromes. Inadequate treatment of nonspecific back pain, even with a relatively favorable prognosis, leads to its chronicity and decreases the patient's quality of life. The most common cause of vertebrogenic dorsopathies is spinal osteochondrosis.
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