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[Chronic pain syndrome in musculoskeletal diseases-how different are fibromyalgia and long Covid?-Part 1].
Z Rheumatol
January 2025
Rheumatologisches Versorgungszentrum Steglitz, Schloßstr. 110, 12163, Berlin, Deutschland.
Chronic pain is a common problem in rheumatology. Nociceptive pain is distinguished from neuropathic and nociplastic pain. Mechanistically, the former is explained by persistent inflammation, for example.
View Article and Find Full Text PDFReply to "Cold urticaria as a complication of cryotherapy in the treatment of viral warts".
Pediatr Dermatol
January 2025
Department of Dermatology, Parc Taulí Hospital Universitari, Sabadell, Spain.
Evaluation of plasma alpha-1-antichymotrypsin as a marker for pulmonary Kaposi sarcoma.
Int J Cancer
January 2025
Department of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.
Individuals with AIDS and Kaposi sarcoma (AIDS-KS) with pulmonary involvement have high-risk of poor outcomes but diagnosis of pulmonary KS in low-resource settings is difficult. We aimed to discover plasma proteins that distinguish individuals with pulmonary KS from those without pulmonary involvement. SomaScan proteomics screen measured 7288 plasma proteins in 22 cases and 17 controls selected from 181 participants with HIV-1 and cutaneous KS who underwent bronchoscopy.
View Article and Find Full Text PDFA Novel Missense Mutation of the ABL1 Gene in a Child With Congenital Heart Defects and Skeletal Malformations Syndrome.
Am J Med Genet A
January 2025
Department of Pulmonology, Children's Hospital of Zhejiang University School of Medicine & National Clinical Research Center for Child Health, Hangzhou, China.
Congenital heart defects and skeletal malformations syndrome (CHDSKM) is a rare autosomal dominant genetic disorder characterized by specific clinical features, including dysmorphic facial traits, congenital heart defects, skeletal abnormalities, joint issues, and failure to thrive. The novelty of this case lies in the identification of a novel mutation in the ABL1 gene, expanding the genetic spectrum associated with this syndrome. A 5.
View Article and Find Full Text PDFBiofluid biomarkers in distinguishing young-onset dementia from primary psychiatric disorders.
Curr Opin Psychiatry
March 2025
Department of Psychiatry, University of Melbourne.
Purpose Of Review: There has been growing interest in the role of biofluid biomarkers to aid the diagnosis of dementia in older people. However, less attention has been given to younger people who have dementia (young-onset dementia), who frequently experience misdiagnoses of primary psychiatric disorders diagnostic delay and challenges accessing appropriate care.
Recent Findings: We describe 12 studies from the previous 2 years of which the majority have investigated the role of neurofilament light chain protein (NfL) in blood and cerebrospinal fluid in distinguishing young-onset dementia from primary psychiatric disorders.
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