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Underestimated latent tuberculosis infection burden among school contacts in China: a cross-sectional study.
Arch Public Health
January 2025
Chongqing Municipal Institute of Tuberculosis, Chongqing, 400045, China.
Background: Previous research has indicated a low tuberculin skin tests (TST) strong positive rate in school tuberculosis (TB) screening implemented by community-level medical and health care institutions in China. The research objective was to evaluate the latent tuberculosis infection (LTBI) detection gap in school contact investigation in China.
Methods: In this cross-sectional study, school contacts were investigated by Chongqing Municipal Institute of Tuberculosis between January 2022 and April 2024 in Chongqing, China.
Update of diagnostic methods in tuberculosis (TB).
Rev Argent Microbiol
January 2025
Servicio de Microbiología, Universidad Católica de Córdoba, Clínica Universitaria Reina Fabiola, Córdoba, Argentina. Electronic address:
The WHO aims to reduce the number of deaths from TB by 95% and decrease its incidence rate by 90% between 2015 and 2035. The recommended rapid diagnostic tests are accurate and cost-effective, allow for a prompt start to treatment, and influence other outcomes that are important to the patient. To detect latent infection, the tuberculin skin test and interferon γ release (IGRA) tests are used.
View Article and Find Full Text PDFEpidemiology of Latent Tuberculosis in Rheumatic Immune-Mediated Inflammatory Diseases-Study of 1117 Patients and Descriptive Literature Review.
J Clin Med
December 2024
Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Avda. Valdecilla s/n., 39008 Santander, Spain.
Patients with rheumatic immune-mediated diseases (rheumatic-IMID) and latent tuberculosis (LTBI) are at an increased risk of developing active tuberculosis (TB); therefore, screening is recommended before starting biological treatment. The aims of this study were as follows: (i) to assess the prevalence of LTBI, (ii) to determine the importance of using a booster test in TST-negative patients, (iii) to compare the tuberculin skin test (TST) with the interferon-gamma release assay (IGRA), (iv) to perform a review of the prevalence of LTBI. A cross-sectional hospital study was performed, including patients diagnosed with rheumatic-IMID who underwent a TST and/or IGRA during the period 2016-2020.
View Article and Find Full Text PDFTHE ROLE OF INTERFERON-GAMMA RELEASE ASSAYS IN DIAGNOSIS OF LATENT TUBERCULOSIS INFECTION IN CHILDREN.
Acta Clin Croat
November 2023
Department of Pulmonology, Allergology, Rheumatology and Clinical Immunology, Zagreb Children's Hospital, Zagreb, Croatia.
Despite numerous published papers, diagnosis of latent tuberculosis infection (LTBI) in children is still an undefined area. The importance of this topic lies in the fact that one third of the world's population is infected with . The majority of infected individuals are LTBI cases which make a reservoir for future active tuberculosis (TB) patients.
View Article and Find Full Text PDFLatent Tuberculosis Infection Management in Solid Organ Transplantation Recipients: A National Snapshot.
Thorac Res Pract
May 2024
Department of Infectious Diseases and Clinical Microbiology, Mersin University Faculty of Medicine, Mersin, Turkey.
Article Synopsis
- Latent tuberculosis infection (LTBI) screening is essential for solid organ transplant (SOT) recipients, but many centers in Turkey are not adequately performing these screenings.
- In a study involving 766 SOT patients, 46.9% tested positive for LTBI, but only about half of those treated were registered, and there was a low completion rate of treatment.
- The findings highlight the need for better TB risk assessment and adherence to national guidelines to improve pre-transplant care for SOT recipients in Turkey.
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