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Reversal of Basal Ganglia Hypermetabolism Following Surgical Removal of Adrenocorticotropic Hormone-Producing Lung Carcinoid in a Patient of Cushing Syndrome With Unusual Presentation of Acute Psychosis: Proof of Concept.
Clin Nucl Med
December 2024
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, India.
Article Synopsis
- A 34-year-old woman diagnosed with severe psychosis also showed signs of Cushing syndrome and underwent an 18 F-FDG PET/CT scan, which identified a hypermetabolic lung lesion and increased brain metabolism in the basal ganglia.
- The lung lesion was surgically removed and confirmed as an adrenocorticotropic hormone-producing lung carcinoid through histopathological analysis.
- After treatment, a follow-up 18 F-FDG PET scan revealed normal brain metabolism and a complete reversal of the psychosis, highlighting the potential for psychosis to be an initial symptom of Cushing syndrome and the usefulness of PET imaging in assessing brain changes.
A Severe Case of Spontaneous Intracranial Hypotension in an Adult Asian Male Improved With Trendelenburg Positioning: A Case Report.
Cureus
May 2024
Institute for Neurosciences, St. Luke's Medical Center, Quezon City, PHL.
Non-traumatic bilateral acute subdural hematomas are a rare occurrence. Etiologies typically include, but are not limited to, cortical artery bleeding, vascular lesions, coagulopathies, and spontaneous intracranial hypotension. We report a case of a 45-year-old Korean male with no known co-morbid illnesses nor history of head or neck trauma, who came to the emergency department due to a 10-day history of dizziness and head heaviness, followed by disorientation and drowsiness.
View Article and Find Full Text PDFCerebral and Muscular Metastases From Prostate Adenocarcinoma Initially Depicted by 177 Lu-PSMA SPECT/CT.
Clin Nucl Med
March 2024
Department of Nuclear Medicine, Klinikum Fulda, Fulda, Germany.
Cerebral and muscular metastases from prostatic adenocarcinoma occur rarely. Patients who develop such metastatic pattern exhibit noticeable symptoms. Herein, we present a 68-year-old man diagnosed with metastatic castrate-resistant prostate cancer.
View Article and Find Full Text PDFDirect comparison of diagnostic and clinical values between Tc-99 m DPD and Tc-99 m PYP scintigraphy in patients with cardiac amyloidosis.
BMC Med Imaging
July 2023
Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Background: Technetium-99 m 3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) and technetium-99 m sodium pyrophosphate (PYP) are the two most commonly used radiotracers for cardiac amyloidosis (CA), but no studies have directly compared them. Therefore, in this study, we directly compared the diagnostic and clinical utility of DPD and PYP scintigraphy in patients with CA.
Methods: Ten patients with CA were enrolled.
The diagnostic performance of functional dopaminergic scintigraphic imaging in the diagnosis of dementia with Lewy bodies: an updated systematic review.
Eur J Nucl Med Mol Imaging
June 2023
Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.
Article Synopsis
- Dopaminergic scintigraphic imaging is crucial for diagnosing dementia with Lewy bodies, and a systematic review was conducted to evaluate its clinical impact.
- The review analyzed 59 studies, focusing on diagnostic performance, distinguishing dementia with Lewy bodies from other dementias, and correlating dopamine transporter loss with clinical outcomes.
- The findings reveal variability in study methodologies and highlight the predominance of the radioligand [123I]N‑ω‑fluoropropyl‑2β‑carbomethoxy‑3β‑(4‑iodophenyl) nortropane (I-FP-CIT) in the imaging studies analyzed.
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