A cataract operation in a young Siberian tiger is reported. This 5-month-old tiger, presenting with blindness, showed bilateral residual pupillary membranes and anterior polar cataracts combined with nuclear cataracts. After unilateral intracapsular extraction of the lens, the tiger adapted well to the improvement in sight and behaved almost like an animal with normal vision. The animal died 3 months post-operatively from unknown cause. Histological examination of the aphakic eye showed, at the site of operation on the cornea, an intact epithelium with discrete infiltration of the stroma together with low-grade vascularisation. In the eye not treated operatively, both an anterior polar cataract with adherent pupillary membrane strands and a central cataract were seen. Of particular note, when comparing this large wild cat with the domestic cat, was the marked development of the tapetum lucidum (up to 30 cell layers).
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http://dx.doi.org/10.1159/000308807 | DOI Listing |
World J Gastrointest Surg
January 2025
Department of Colorectal Surgery, Sir Run Shaw Hospital Affiliated with Zhejiang University, Hangzhou 310016, Zhejiang Province, China.
Background: Despite improved survival rates in rectal cancer treatment, many patients experience low anterior resection syndrome (LARS). The preoperative LARS score (POLARS) aims to address the limitations of LARS assessment by predicting outcomes preoperatively to enhance surgical planning.
Aim: To investigate the predictive accuracy of POLARS in assessing the occurrence of LARS.
Cell Signal
January 2025
Department of Cardiovascular Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China; Future Medical laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China. Electronic address:
Background: Dichloroacetate (DCA) has shown potential in modulating cellular metabolism and inflammation, particularly in cardiac conditions. This study investigates DCA's protective effects in a mouse model of myocardial infarction (MI), focusing on its ability to enhance cardiac function, reduce inflammation, and shift macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype.
Methods: An acute MI model was created using left anterior descending coronary artery ligation.
Acta Parasitol
January 2025
Laboratory of Parasitology and Ecology, Department of Animal Biology and Physiology, Faculty of Sciences, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon.
Purpose: Fish are susceptible to various parasitic infections, with Myxozoa emerging as a major group. A taxonomic study of Myxozoa is essential for the rapid diagnosis of species potentially responsible for epizootic diseases.
Methods: The studied fish was collected from the Kadey River, a tributary of the Sangha River in the Congo Basin in Cameroon, and parasitologically dissected.
J Cell Biol
April 2025
Department of Physics and Astronomy, University of Denver, Denver, CO, USA.
In the early Drosophila embryo, germband elongation is driven by oriented cell intercalation through t1 transitions, where vertical (dorsal-ventral aligned) interfaces contract and then resolve into new horizontal (anterior-posterior aligned) interfaces. Here, we show that contractile events produce a continuous "rectification" of cell interfaces, in which interfaces systematically rotate toward more vertical orientations. As interfaces rotate, their behavior transitions from elongating to contractile regimes, indicating that the planar polarized identities of cell-cell interfaces are continuously re-interpreted in time depending on their orientation angle.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Background: Polydatin (PD), also known as tiger cane glycoside, is a natural compound extracted from the Japanese knotweed plant, which is often referred to as white resveratrol. It exhibits anti-inflammatory, antioxidant, and anti-apoptotic effects in the treatment of various diseases. However, the potential molecular mechanisms of PD in osteoarthritis have not been clearly elucidated.
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