Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1515/znb-1972-1120 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mechanism of dsDNA binding, enzyme inhibition, antioxidant activities, and molecular docking studies of taxifolin, daidzein, and S-equol.
Int J Biol Macromol
January 2025
Afsin Vocational School, Department of Chemistry and Chemical Processing Technologies, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey. Electronic address:
This study investigated the binding mechanism of taxifolin (TA), daidzein (DA), and S-equol (SQ) flavonoids with fish sperm double helix DNA (dsDNA) under the simulated physiological pH condition using UV-Vis and photoluminescence spectroscopy, as well as viscometric methods. Binding constants (K) for the flavonoids to dsDNA were determined as 1.8 × 10 M for SQ, 1.
View Article and Find Full Text PDFUnderstanding how vitamins and fertilizers interact in aquatic environments is crucial for managing water quality, protecting aquatic life, and promoting sustainable agricultural practices. The molecular interactions between nicotinamide (NA) and two fertilizers, potassium chloride (KCl) and diammonium hydrogen phosphate (DAP), were examined by density () and viscosity () measurements in order to investigate and analyze the solvation behavior that occurs in the ternary solutions (NA + KCl/DAP + water). All of these investigations were conducted at temperatures ranging from 293.
View Article and Find Full Text PDFInfluence of Parameters Used to Prepare Sterile Solutions of Poloxamer 188 on Their Physicochemical Properties.
Polymers (Basel)
December 2024
Institute of Theoretical and Experimental Biophysics RAS, Pushchino 142290, Russia.
The physicochemical properties of emulsions based on poloxamers (triblock copolymers of a hydrophobic polyoxypropylene chain and two hydrophilic polyoxyethylene chains) depend on the composition and preparation method. This study examined the impact of poloxamer P188 concentration, autoclaving mode, heating, and salt presence on the viscosity, particle size distribution, and morphology of particles using viscometric analysis, dynamic light scattering (DLS), and atomic force microscopy (AFM). It was shown that sample preparation affects the particle size and morphology but not the chemical composition of P188.
View Article and Find Full Text PDFInvestigation of mono-nuclear cobalt(II) complexes with a tri-dentate quinoxalyl-hydrazone ligand for their potential in biological research and interaction with ct-DNA.
Int J Biol Macromol
February 2025
Department of Chemistry, Faculty of Science, Sohag University, Sohag, -82534, Egypt; Department of Chemistry, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia. Electronic address:
The condensing reaction of 2-hydroxy-1-naphthaldehyde with quinoxalyl-2-carbohydrazide resulted in synthesizing of a novel derivative of hydrazone quinoxalyl ligand (Hdpq). The bonding behavior between Hdpq and Co(II) ion was investigated in molar ratios of 1: 1 and 2: 1 to produce two different complexes, Codpq and Co(dpq), respectively. Their chemical structure was verified using several spectroscopic approaches.
View Article and Find Full Text PDFNucleic acid binding affinity and antioxidant activity of N-m-Tolyl-4-Chlorophenoxyacetohydroxamicacid.
Sci Rep
September 2024
Department of Chemistry, Bhairab Ganguly College, Kolkata, West Bengal, India.
Hydroxamic acids represent a group of weak organic acids, both naturally occurring and synthetically derived, characterized by the general formula RC(= O)N(R'OH). In this study, we investigated the binding behavior of N-m-tolyl-4-chlorophenoxyaceto hydroxamic acid with calf thymus DNA (ct-DNA) and torula yeast RNA (t-RNA) through a combination of techniques including UV-visible spectroscopy, fluorescence emission analysis, viscometry, and computational simulations using AutoDock4 software. Our findings reveal that the mode of binding between the compound and the nucleic acids is consistent with intercalation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!