It is shown that during the saturation of steroid carbon-carbon double bonds at Delta(24,25) and Delta(14,15) the ;hydride ion' originates from the 4B side of the NADPH.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1179453PMC
http://dx.doi.org/10.1042/bj1190673DOI Listing

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