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Kounis syndrome following COVID-19 vaccination: Clinical manifestations, mechanisms and management.
Hum Vaccin Immunother
December 2024
Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Kounis syndrome is an acute coronary syndrome triggered by allergic mediators that induce coronary vasoconstriction and thrombosis, leading to further myocardial damage and anaphylactic shock. Kounis syndrome is also a rare but severe adverse reaction to the COVID-19 vaccine, a phenomenon that underscores the importance of collecting and analyzing similar cases to improve treatment and prognosis. Through comprehensive searches of the Web of Science, Embase, and PubMed databases, this study aimed to gather detailed patient data on patients who developed Kounis syndrome after receiving the COVID-19 vaccine and to further investigate the possible underlying mechanisms using currently available studies.
View Article and Find Full Text PDFPerioperative anaphylaxis associated with peripheral inserted central catheter: A retrospective observational study.
J Vasc Access
December 2024
Department of Catheter Clinic, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P.R. China.
Article Synopsis
- - The use of Peripheral Inserted Central Catheters (PICC) for long-term intravenous therapy is rising, but there’s an alarming increase in anaphylaxis cases linked to this procedure.
- - A study at Sun Yat-sen University Cancer Center from January 2021 to August 2023 found that 0.10% of cancer patients experienced anaphylactic reactions during PICC placement, typically lasting around 8 minutes.
- - There is a call for heightened awareness and research among healthcare providers to identify what triggers these reactions and to develop better prevention strategies.
Occupational anaphylaxis: A Position Paper of the German Society of Allergology and Clinical Immunology (DGAKI).
Allergol Select
November 2024
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich TUM).
Background: Anaphylaxis is a systemic allergic reaction that is potentially life-threatening. Occupational anaphylaxis is an anaphylaxis that occurs in an occupational context. In this position paper, we propose diagnostic criteria for occupational anaphylaxis and provide an overview of the current state of knowledge in terms of prevalence, triggers, prevention, and management.
View Article and Find Full Text PDFA real-world disproportionality analysis of FDA Adverse Event Reporting System (FAERS) events for ramucirumab.
Expert Opin Drug Saf
December 2024
Department of Pharmacy, Pingtan Comprehensive Experimental Area Hospital, Fuzhou, PR China.
Background: Ramucirumab (IMC-1121B) is a fully human immunoglobulin G1 monoclonal antibody, approved by the US Food and Drug Administration (FDA) for treating various cancers, including gastric, colorectal, liver, and non-small cell lung cancer. This study aimed to investigate the adverse events (AEs) associated with ramucirumab by utilizing data mining techniques on the FDA Adverse Event Reporting System (FAERS).
Methods: We collected ramucirumab-related data from the FAERS database, spanning from January 2014 to June 2023.
The Use of Botulinum Toxin Type A and the Occurrence of Anaphylaxis: A Descriptive Analysis of Data from the European Spontaneous Reporting System.
Aesthetic Plast Surg
December 2024
Multidisciplinary Department of Medical Surgery and Dental Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Background: Botulinum toxin type A (BTA) is a protein produced by Clostridium botulinum bacteria. It is the most widely used among botulinum toxin types, and it is recommended for the treatment of many clinical conditions, including muscle hyperactivity syndromes and for esthetic indications too. BTA is generally considered safe, and the most reported adverse events (AEs) include eyelids ptosis, immunogenicity, neuromuscular disorders and hypersensitivity reactions.
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