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Cutoffs on severity metrics for minimal manifestations or better status in patients with generalized myasthenia gravis.
Front Immunol
January 2025
Department of Neurology, Hanamaki General Hospital, Hanamaki, Japan.
International consensus guidance and Japanese clinical guidelines for myasthenia gravis (MG) recommend achieving minimal manifestations or better status (MM-or-better) as the severity component of the treatment goal. However, the subjective nature of determining MM can result in ambiguity regarding this category in clinical practice and clinical trials. This study analyzed severity metrics in a large number of MG patients to propose criteria for MM-or-better.
View Article and Find Full Text PDFAssessment of the methodological quality of studies on core outcome sets for respiratory diseases: A systematic review and meta-research study.
PLoS One
January 2025
Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-constructed by Henan Province & Education Ministry of P.R. China/Henan Key Laboratory of Chinese Medicine for Respiratory Diseases, Henan University of Chinese Medicine, Zhengzhou, China.
Background: With increasing attention to core outcome sets (COS), the number of studies on COS for respiratory diseases (COS-RD) is on the rise. However, the methodological quality is still unclear. Therefore, we conducted a study to assess the methodological quality of studies on COS-RD.
View Article and Find Full Text PDFChinese translation, cross-cultural adaptation, and psychometric validation of patient-reported outcome measurement- questionnaire about gynecological and pelvic pain symptoms (ENDOPAIN-4D).
Eur J Obstet Gynecol Reprod Biol
December 2024
Gynecology Ward 1, Chinese Academy of Medical Sciences & Peking Union Medical College Hospital, Beijing, China.
Objectives: The aim of this study was to cross-culturally translate a questionnaire about gynecological and pelvic pain symptoms (ENDOPAIN-4D) patient-reported outcome measurement (PROM) into Chinese and evaluate its reliability and validity.
Methods: The questionnaire was translated according to Brislin's classic back-translation model. We conducted cultural debugging through cognitive interviews with Chinese-speaking women who had experienced pelvic pain (n = 24).
Clinical Outcome Assessments for Spasticity: Review, Critique, and Recommendations.
Mov Disord
December 2024
Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Background: Spasticity is a common feature in patients with disruptions in corticospinal pathways. However, the term is used ambiguously. Here, spasticity is defined as enhanced velocity-dependent stretch reflexes and placed within the context of deforming spastic paresis encompassing other forms of muscle overactivity.
View Article and Find Full Text PDFDiscriminant Validity of Interval Response Formats: Investigating the Dimensional Structure of Interval Widths.
Educ Psychol Meas
November 2024
University of Marburg, Germany.
In psychological research, respondents are usually asked to answer questions with a single response value. A useful alternative are interval response formats like the dual-range slider (DRS) where respondents provide an interval with a lower and an upper bound for each item. Interval responses may be used to measure psychological constructs such as variability in the domain of personality (e.
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