A cycloheximide-resistant mutant was isolated from the amoeba Acanthamoeba castellanii Neff. Drug resistance was found to be due to a ribosomal modification.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC218274PMC
http://dx.doi.org/10.1128/jb.138.1.280-283.1979DOI Listing

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