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Early and Late Microvascular Inflammation Have Differing Etiological Causes and Clinical Expression.
Transplantation
September 2024
Department of Tissue Pathology and Diagnostic Oncology, ICPMR, Westmead Hospital, Westmead, NSW, Australia.
Background: Microvascular inflammation (MVI) is an important pathological feature of antibody-mediated rejection (AMR). How posttransplant time affects its clinicopathological expression is little understood.
Methods: This retrospective, single-center study screened 3398 kidney transplant biopsies and dichotomized 202 MVI ≥ 2 (Banff glomerulitis + peritubular capillaritis ≥ 2) samples by 9-mo median incidence time for comparison.
COVID-19 frequency and clinical course in children with asthma.
World J Virol
December 2023
Department of Pediatric Allergy and Immunology, Sakarya University, Adapazarı 54100, Sakarya, Türkiye.
Background: The epidemic of severe acute respiratory syndrome coronavirus 2 infection, known as the coronavirus disease 2019 (COVID-19), has caused a global health concern. Since its emergence, numerous studies have focused on various clinical manifestations and outcomes in different populations. However, studies are ongoing as the consequences and impact of COVID-19 in children with chronic diseases such as asthma are controversial.
View Article and Find Full Text PDFAntibodies against complement component C5 prevent antibody-mediated rejection after lung transplantation in murine orthotopic models with skin-graft-induced pre-sensitization.
Gen Thorac Cardiovasc Surg
December 2022
Department of General Thoracic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chiba, Japan.
Objective: Antibody-mediated rejection (AMR) could induce acute or chronic graft failure during organ transplantation. Several reports have shown that anti-C5 antibodies are effective against AMR after kidney transplantation. However, few reports have assessed the efficacy of anti-C5 antibodies against AMR after lung transplantation.
View Article and Find Full Text PDFAmelioration of Ovalbumin-Induced Allergic Asthma by via Downregulation of Inflammatory Cytokines and Upregulation of Aquaporin-1 and Aquaporin-5 in Mice.
J Trop Med
March 2022
Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
() has been used traditionally to treat cough and asthma. The present study evaluates the immunomodulatory and anti-inflammatory potential of against ovalbumin (OVA)-induced allergic asthma. Intraperitoneal sensitization proceeded by intranasal challenge with OVA was used to induce allergic asthma.
View Article and Find Full Text PDFAnti-asthmatic effect of Juglans regia Linn. in mice.
Pak J Pharm Sci
March 2021
Department of Pharmacology, Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
Plants are considered as an essential source to treat different diseases. In traditional system of medicine, Juglans regia (J. regia) has been used in curing sinusitis and cough.
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