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Chinese yam (Dioscorea opposita Thunb.) starch-ferulic acid complexes: Preparation, characterization, and physicochemical properties.
J Food Sci
January 2025
School of Life Sciences and Chemistry, Minnan Science and Technology College, Quanzhou, Fujian, China.
Polyphenols are known to interact with starch to form the V-type inclusion complex or the noninclusive complex. It is hypothesized that the addition of polyphenols could improve the properties of Chinese yam (Dioscorea opposita Thunb.) starch, and the properties of the complexes could be regulated by controlling the additive amount of polyphenols.
View Article and Find Full Text PDFMolecular modeling aided design, synthesis and biological evaluation of quinazoline derivatives for the treatment of human cancer.
Mol Divers
January 2025
School of Biological & Chemical Engineering, Zhejiang University of Science & Technology, Hangzhou, 310023, People's Republic of China.
The quinazoline scaffold serves as a fundamental framework, demonstrating potent anti-tumor activity. Employing the pharmacophore-based scaffold hopping principle, we successfully synthesized a series of FAK/PLK1 inhibitors incorporating the quinazoline scaffold. The synthesized compounds were characterized using H NMR, C NMR, and HRMS techniques.
View Article and Find Full Text PDFEnabling icIEF Peak Identification of AAV Capsid Proteins by Fractionation on MauriceFlex and Subsequent Analysis by LC-MS.
Electrophoresis
January 2025
Pfizer, Analytical Research and Development, Chesterfield, Missouri, USA.
A significant limitation of imaged capillary electric focusing (icIEF) is the inability to identify and characterize specific species in the electropherogram. This has led to the development of complementary ion-exchange chromatography (IEX)-based methods that are amenable to either fraction collection and subsequent characterization or online IEX coupled to mass spectrometry. To overcome this limitation while maintaining the use of icIEF, novel approaches, including an icIEF separation and fractionation technology (MauriceFlex, ProteinSimple), have been developed.
View Article and Find Full Text PDFPreparation of protein and its preventive effect on nonalcoholic fatty liver disease in mice.
Food Funct
January 2025
Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, National Engineering Research Center of Edible Fungi, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, 201403, China.
is a valuable edible fungus with multidimensional bioactivities; however, research on protein and its beneficial effects on nonalcoholic fatty liver disease (NAFLD) have been limited. In this study, protein (MEP) with 80.59% protein content was prepared, isolated, and characterized by the complete amino acid composition.
View Article and Find Full Text PDFVisible light induced photocatalytic degradation of norfloxacin using xC-TiO.
Heliyon
January 2025
Institute of Chemical Sciences, University of Swat, Swat, 19120, Khyber Pakhtunkhwa, Pakistan.
In recent years, antibiotic pollution has become a major environmental concern. The extensive production and widespread use of prescribed antibiotics have significantly impacted ecosystems. The main objective of the present study is to investigate the photocatalytic degradation of the antibiotic norfloxacin (NFX) under visible light.
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