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Some technical limitations to using the eccentric mode to measure peak eccentric strength of the hamstrings (PTH) were raised. PTH also has limited validity to predict performance or injury risk factor. Therefore, our aim was to compare PTH and other isokinetic variables tested in the eccentric and passive modes.

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Advances in liver organoids: replicating hepatic complexity for toxicity assessment and disease modeling.

Stem Cell Res Ther

January 2025

Organoid Innovation Center, Suzhou Institute of Nanotech and Nano-bionics, Chinese Academy of Sciences, 398 Ruoshui Rd, Suzhou, Jiangsu, 215123, China.

The lack of in vivo accurate human liver models hinders the investigation of liver-related diseases, injuries, and drug-related toxicity, posing challenges for both basic research and clinical applications. Traditional cellular and animal models, while widely used, have significant limitations in replicating the liver's complex responses to various stressors. Liver organoids derived from human pluripotent stem cells, adult stem cells primary cells, or tissues can mimic diverse liver cell types, major physiological functions, and architectural features.

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Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting millions worldwide, leading to cognitive and functional decline. Early detection and intervention are crucial for enhancing the quality of life of patients and their families. Remote Monitoring Technologies (RMTs) offer a promising solution for early detection by tracking changes in behavioral and cognitive functions, such as memory, language, and problem-solving skills.

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Background: Male knowledge and acceptance of modern contraceptive use play a significant role in uptake. This study assessed the factors associated with male acceptance of modern contraceptive methods in Ho Municipality.

Methods: A cross-sectional study with a quantitative approach was employed.

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This in-vitro study assessed the influence of the shade of human teeth on the transmission of near-infrared light. A total of 40 teeth were used. After cleaning the root surface and removing cementum, the teeth were sectioned into slices 3 mm thick, with each comprising a portion of the crown (enamel-dentine (ED)) and of the root (dentine only).

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