Twenty-one of 29 patients suffering from myasthenia gravis derived benefit from a short intensive course of adrenocorticotrophin (ACTH). The mean duration of benefit was approximately six months. The best results were obtained in patients with a short history of myasthenia. Transient deterioration during the course of injections was encountered in some cases but necessitated assisted respiration only in patients with severe generalized weakness before treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC494671PMC
http://dx.doi.org/10.1136/jnnp.37.4.412DOI Listing

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