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The associations between cardiovascular and pain responses to a cold pressor test differ between males and females.
Eur J Appl Physiol
January 2025
Department of Physical Therapy & Rehabilitation Science, Carver College of Medicine, the University of Iowa, Iowa City, IA, 52242, USA.
Nociceptors contribute to the cardiovascular responses during a cold pressor test (CPT). While these responses are lower in females, data suggest that they perceive the CPT as more painful. Thus, we examined sex differences in associations between pain and cardiovascular responses to a CPT (Aim 1) as well as differences between females using (OC), and not using (NC), an oral contraceptive (Aim 2).
View Article and Find Full Text PDFResting beat-to-beat blood pressure variability in humans: role of alpha-1 adrenergic receptors.
Clin Auton Res
January 2025
Department of Health and Kinesiology, Purdue University, West Lafayette, Indiana, USA.
Purpose: Resting beat-to-beat blood pressure variability is a strong predictor of cardiovascular events and mortality. However, its underlying mechanisms remain incompletely understood. Given that the sympathetic nervous system plays a pivotal role in cardiovascular regulation, we hypothesized that alpha-1 adrenergic receptors (the main sympathetic receptor controlling peripheral vasoconstriction) may contribute to resting beat-to-beat blood pressure variability.
View Article and Find Full Text PDFA Method for Imaging the Ischemic Penumbra with MRI using IVIM.
AJNR Am J Neuroradiol
January 2025
From the Department of Radiology, Medical Physics (MML, TJC), Department of Interventional Radiology (NS, GAC), Department of Surgery and Large Animal Studies (MAN), and the Department of Statistics (MG), University of Chicago, Chicago, IL, USA; Department of Anesthesiology (SPR), University of Illinois, Chicago, IL, USA; Department of Radiology (MSS), University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Radiology, Biomedical Engineering and Imaging Institute (Current affiliation MML), Icahn School of Medicine at Mount Sinai, New York, NY, USA; Mount Carmel Health Systems (Current affiliation GAC), Columbus, OH, USA.
Background And Purpose: In acute ischemic stroke, the amount of "local" CBF distal to the occlusion, i.e. all blood flow within a region whether supplied antegrade or delayed and dispersed through the collateral network, may contain valuable information regarding infarct growth rate and treatment response.
View Article and Find Full Text PDFStress Appraisal, Stress Mindset, and Perceived Pain During a Cold Pressor Test.
Int J Behav Med
January 2025
Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands.
Background: Previous studies demonstrated that task-specific stress appraisals as well as the more general belief that stress is (mal)adaptive (i.e., stress mindset) can affect the stress response.
View Article and Find Full Text PDFIdentifying the most effective acute stress induction methods for producing SAM- and HPA-related physiological responses: a meta-analysis.
Anxiety Stress Coping
January 2025
Neuroendocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Background And Objectives: Laboratory-based stress inductions are commonly used to elicit acute stress but vary widely in their procedures and effectiveness. We compared the effects of stress induction techniques on measures of two major biological stress systems: the early sympathetic-adrenal-medullary (SAM) and the delayed hypothalamic-pituitary-adrenal (HPA) axis response.
Design: A review and meta-analysis to examine the relationship between stress induction techniques on cardiorespiratory and salivary measures of SAM and HPA system activity.
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