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Single and combined chronic toxicity of cadmium and titanium dioxide nanoparticles in Aquarana catesbeiana (Anura: Ranidae) tadpoles.
Aquat Toxicol
January 2025
Department of Morphology, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil. Electronic address:
The rising production and improper disposal of titanium dioxide nanoparticles (TiO NPs) into aquatic systems present considerable environmental challenges, especially when these particles interact with other contaminants such as cadmium (Cd). Thus, the current study aimed to evaluate the potential toxic effects on the gills, chondrocranium, body growth, and mortality of Aquarana catesbeiana tadpoles. The tadpoles were exposed to environmentally relevant concentrations of TiO NPs (10 µg L), and CdCl (10 µg L), both individually and in combination, for 30 days (chronic exposure), along with a control group.
View Article and Find Full Text PDFMethimazole disrupted skeletal ossification and muscle fiber transition in Bufo gargarizans larvae.
Ecotoxicol Environ Saf
January 2025
Life and Environmental Science College, Wenzhou University, Wenzhou 325003, China; Zhejiang Provincial Key Laboratory for Subtropical Water Environment and Marine Biological Resources Protection, Wenzhou University, Wenzhou 325003, China. Electronic address:
Methimazole (MMI) is an emerging endocrine disrupting chemical (EDC) due to its increasing use in the treatment of thyrotoxicosis (hyperthyroidism), but its potential impact on amphibian development remains largely unexplored. In the present study, the effects of 8 mg/L MMI and 1 μg/L thyroxine (T4) exposure on skeletal ossification and muscle development in Bufo gargarizans tadpoles were comprehensively investigated by double skeletal staining, histological analysis and RNA sequencing. Our results indicated that MMI treatment down-regulated the expression levels of ossification-related genes (e.
View Article and Find Full Text PDFDoes force depression resulting from shortening against series elasticity contribute to the activation dependence of optimum length?
Am J Physiol Cell Physiol
February 2025
Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, California, United States.
The optimum length for force generation () increases as activation is reduced, challenging classic theories of muscle contraction. Although the activation dependence of is seemingly consistent with length-dependent Ca sensitivity, this mechanism cannot explain the apparent force dependence of or the effect of series compliance on activation-related shifts in . We have tested a theory proposing that the activation dependence of relates to force depression resulting from shortening against series elasticity.
View Article and Find Full Text PDFMinimally invasive treatment of grade I and II gluteal muscle contracture using a self-made special cutter combined with a specialized compression hemostasis device.
BMC Musculoskelet Disord
December 2024
Department of Orthopedics, Sihong Hospital, Sihong, Jiangsu Province, China.
Background: To explore the method and curative effect of minimally invasive treatment of gluteal muscle contracture (GMC) with self-made special cutter combined with special compression hemostasis device.
Methods: The data of 88 patients with GMC treated in our hospital from May 2017 to January 2021 were analyzed retrospectively. They were divided into two groups according to different surgical instruments and hemostatic devices.
Frog Fibres: What Muscle Architecture Can Tell Us About Anuran Locomotor Function.
J Morphol
January 2025
Centre for Integrative Anatomy, Cell and Developmental Biology, University College London, Bloomsbury, London, UK.
Muscle fibre architecture is an important aspect of anatomy to consider when estimating muscle properties. How fibre architecture varies across species specialising in different locomotor functions is not well understood in anurans, due to difficulties associated with fibre extraction in small animals using traditional methods. This paper presents the first digital analysis of fibre architecture in frogs using an automated fibre-tracking algorithm and contrast-enhanced µCT scans.
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