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Vulvar Epidermolytic Hyperkeratosis: A Comprehensive Systematic Review of Case Reports and Series.
J Clin Med
December 2024
Department of Oncologic Dermatology-Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
: Vulvar epidermolytic hyperkeratosis (EHK) is an exceedingly rare dermatological condition, often presenting as solitary or multiple lesions in the vulvar region. Due to its clinical resemblance to other vulvar disorders, such as condyloma acuminatum, Bowenoid papulosis, and squamous cell carcinoma, vulvar EHK poses significant diagnostic challenges. While individual case reports and small case series have documented instances of vulvar EHK, comprehensive studies systematically consolidating the clinical, histopathological, and therapeutic aspects of this condition remain lacking.
View Article and Find Full Text PDFOral Manifestations in Paraneoplastic Syndromes: A Systematic Review and Meta-Analysis.
Oral Dis
October 2024
Interdisciplinary Department of Medicine, University of Bari, Bari, Italy.
Article Synopsis
- This study investigated the oral signs and symptoms associated with paraneoplastic syndromes by analyzing data from various medical databases.
- A systematic review found that common oral issues included conditions like paraneoplastic pemphigus, mucous membrane pemphigoid, and acanthosis nigricans, with the palate being the most affected area.
- The findings indicate a high prevalence of mortality (50.9%) and a notable remission rate (63.4%) after treatment, highlighting the need for further research to improve diagnosis and patient care.
Cutaneous findings in patients with acromegaly and its relationship with concomitant endocrinopathies.
Clin Endocrinol (Oxf)
September 2024
Department of Endocrinology and Metabolism, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Article Synopsis
- The study aimed to explore skin changes in patients with acromegaly, a condition often revealed through dermatological symptoms, and examine how these changes relate to disease remission and other hormonal disorders.
- Involving 278 acromegaly patients across 14 healthcare centers, dermatological evaluations revealed common skin conditions like skin tags (52.5%), cherry angiomas (47.4%), and varicose veins (33%).
- Significant associations were found between certain skin conditions and hormonal issues, such as higher rates of diabetes and hypothyroidism in patients with varicose veins, while hypertrichosis was more common in patients who had not achieved remission.
Pemphigus Vegetans of Hallopeau: A Case Report.
Acta Dermatovenerol Croat
August 2023
Jelena Maljić, MD, University Hospital Centre Zagreb, Zagreb, Croatia;
Dear Editor, Pemphigus vegetans (PV) of Hallopeau is a rare and indolent variant of pemphigus clinically characterized by vegetating lesions preceded by pustules mainly in flexural areas (1,2). This helps us to differentiate it from PV of Neumann, which is a more extensive and refractory disease, more alike to a pemphigus vulgaris outbreak with blisters which turn into vegetating plaques (3). We report the clinical presentation, course, and therapeutic response in a patient diagnosed with PV of Hallopeau from its early stage during a 3-year follow up.
View Article and Find Full Text PDFClinical factors associated with remission of obese acanthosis nigricans after laparoscopic sleeve gastrectomy: a prospective cohort study.
Int J Surg
December 2023
Department of General Surgery.
Background: Acanthosis nigricans (AN) involves skin hyperpigmentation in body folds and creases. Obesity-associated AN (OB_AN) is the most common type of AN. The skin condition of obese patients with AN can be improved through bariatric surgery, such as laparoscopic sleeve gastrectomy (LSG), after weight loss.
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