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Endovascular Thrombectomy for Extracranial Internal Carotid Artery Occlusions With Large Ischemic Strokes: Insights From the SELECT2 Trial.
Neurology
February 2025
Department of Neurology, Department of Stroke, University Hospital Cleveland Medical Center, Case Western Reserve University, Cleveland, OH.
Background And Objectives: Although previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most of them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We aimed to compare outcomes in patients with e-ICA occlusion and large ischemic core infarcts treated with EVT vs medical management (MM).
Methods: This was a secondary analysis of the SELECT2 trial, a randomized controlled trial conducted at 31 international sites.
Unlabelled: Accurate localization of white matter pathways using diffusion MRI is critical to investigating brain connectivity, but the accuracy of current methods is not thoroughly understood. A fruitful approach to validating accuracy is to consider microscopy data that have been co-registered with MRI of post mortem samples. In this setting, structure tensor analysis is a standard approach to computing local orientations for validation.
View Article and Find Full Text PDFCorkscrew esophagus in an elderly patient: A case of diffuse esophageal spasm with literature review.
Radiol Case Rep
March 2025
College of Medicine, University of Baghdad, Baghdad, Iraq.
Diffuse esophageal spasm (DES) is a rare motility disorder characterized by uncoordinated esophageal contractions, often presenting with dysphagia and chest pain. This case describes a 70-year-old male who presented with atypical symptoms of DES, including episodic dysphagia to solids, postprandial vomiting, and chest pain triggered by cold liquids. Initially misdiagnosed as indigestion, further evaluation with barium swallow imaging revealed a "corkscrew" esophagus, leading to the diagnosis of DES.
View Article and Find Full Text PDFTransformative social innovation and rural collaborative workspaces: assembling community economies in Austria and Greece.
Open Res Eur
January 2025
Department of Economic and Regional Development,, Panteion University of Social and Political Sciences, Athens, L. Syggrou 136, 16761, Greece.
Background: Collaborative Workspaces are rapidly growing and evolving across the world. Traditionally understood as an urban phenomenon, most research understands them as either 'entrepreneurial-led', as profit-driven and commercial spaces such as business incubators and accelerators, or 'community-led' as being bottom-up, not-for-profit ventures aimed at catering for the needs of their community. Recent years however have seen their diffusion beyond large urban agglomerations to small towns and villages, with their functions assumed to be more community-orientated.
View Article and Find Full Text PDFDiffuse Alveolar Hemorrhage Associated With Anti-PL-7 Antisynthetase Syndrome: A Case Report.
Case Rep Pulmonol
January 2025
Prisma Health, University of South Carolina-School of Medicine, Columbia, South Carolina, USA.
Diffuse alveolar hemorrhage (DAH) is a potentially life-threatening condition which can present with hemoptysis, diffuse alveolar infiltrates, anemia, and hypoxic respiratory failure. Antisynthetase syndrome (AS) is a rare autoimmune disorder most often characterized by nonerosive arthritis, proximal muscle weakness with elevated muscle enzymes, Raynaud's phenomenon, hyperkeratosis of the digits (mechanic's hands), and interstitial lung disease. According to large population studies, AS has an annual incidence of 0.
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