AI Article Synopsis
- The study analyzed prostaglandin levels in the antrum and fundus of rats after performing vagotomies.
- The fundus showed significantly higher prostaglandin E1 levels compared to the antrum.
- There was no observable effect of vagotomy on prostaglandin levels, indicating no conclusion could be drawn about vagotomy causing increased levels.
Article Abstract
To determine tissue prostaglandin levels in antrum and fundus and to examine the effect of vagotomy and distention on tissue prostaglandin levels, truncal and parietal cell vagotomies were performed on rats that were killed at 2, 4, and 6 weeks postoperatively with antral and fundic prostaglandin E1 levels being determined. The fundus has considerably higher levels of prostaglandin than the antrum. No differences after any type of vagotomy however, were noted. It cannot be concluded from this study that increased prostaglandin levels result from vagotomy.
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| http://dx.doi.org/10.1001/archsurg.1979.01370270101019 | DOI Listing |
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