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Sci Rep
January 2025
Departamento de Ciencias de la Construcción, Facultad de Ciencias de la Construcción Ordenamiento Territorial, Universidad Tecnológica Metropolitana, Santiago, Chile.
There is an initiative driven by the carbon-neutrality nature of biochar in recent times, where various countries across Europe and North America have introduced perks to encourage the production of biochar for construction purposes. This objective aligns with the zero greenhouse emission targets set by COP27 for 2050. This research work seeks to assess the effectiveness of biochar in soils with varying grain size distributions in enhancing the soil-water characteristic curve (SWCC).
View Article and Find Full Text PDFACS Biomater Sci Eng
January 2025
Weldon School of Biomedical Engineering, Purdue University, West Lafayette 47907-2050, Indiana, United States.
Granular hydrogels are injectable and inherently porous biomaterials assembled through the packing of microparticles. These particles typically have a symmetric and spherical shape. However, recent studies have shown that asymmetric particles with high aspect ratios, such as fibers and rods, can significantly improve the mechanics, structure, and cell-guidance ability of granular hydrogels.
View Article and Find Full Text PDFBackground: Phosphorylated tau proteins accumulate in pathological aggregates which define neurodegenerative tauopathies, including Alzheimer's disease (AD). Insight into the early stages of tau polymerization/aggregation, including early hyperphosphorylation events, is critical for identification of biomarkers of incipient disease as well as novel therapy targets.
Method: We analyzed postmortem tissue sections of hippocampus from AD cases and middle frontal gyrus from non-AD cases with mainly 4R tau isoforms (progressive supranuclear palsy, PSP; corticobasal degeneration, CBD; aging related tau astrogliopathy, ARTAG) or 3R tau (Pick's disease, PiD).
Soft Matter
January 2025
Department of Mechanical Engineering & Materials Science, Washington University, St. Louis, USA.
Epithelial cell collectives migrate through tissue interfaces and crevices to orchestrate development processes, tumor invasion, and wound healing. Naturally, the traversal of cell collective through confining environments involves crowding due to narrowing spaces, which seems tenuous given the conventional inverse relationship between cell density and migration. However, the physical transitions required to overcome such epithelial densification for migration across confinements remain unclear.
View Article and Find Full Text PDFClin Nephrol Case Stud
December 2024
Nephrology Center and the Okinaka Memorial Institute for Medical Research.
A 47-year-old woman with a 12-year history of anemia and high C-reactive protein (CRP) levels was admitted to our hospital with worsening fatigue and night sweats. She had high levels of immunoglobulin G (IgG; 4182 mg/dL), IgA (630.6 mg/dL), and CRP (7.
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