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Salivary IgA levels and infection risk in elite swimmers.
Med Sci Sports Exerc
January 1999
Hunter Immunology Unit, Royal Newcastle Hospital, NSW, Australia.
Unlabelled: The effects of exercise on the immune system has been shown to be dependent on the level of fitness of the subjects, the degree of intensity, and the duration of the exercise. A reduction in salivary IgA levels occurs after individual sessions of exercise.
Purpose: The purpose of this study was to assess the relationship between changes in salivary IgA and training volume, psychological stress, and infection rates in a cohort of 26 elite swimmers over a 7-month training period and to compare the changes with a group of 12 moderately exercising controls.
Von Willebrand factor abnormalities in IgA nephropathy.
Nephrol Dial Transplant
March 1997
Institute of Internal Medicine, School of Medicine, University of Padua, Italy.
Background: Plasma concentration of von Willebrand factor (vWF) has been used as an index of endothelial dysfunction. Increased release of vWF from endothelial cells has been reported in several conditions, and there is also evidence that dysfunctioning endothelial cells synthesize defective molecules. In fact, unusually large vWF multimers have been described and related to the pathogenesis of some microangiopathic diseases.
View Article and Find Full Text PDFCorrection factors for single radial immunodiffusion and electroimmunodiffusion assays of IgA in secretory fluids.
Clin Chim Acta
February 1993
Laboratoire de Biologie Animale et Parasitaire, UER René Descartes, Paris, France.
A comparison of secretory antibodies in breast-fed and formula-fed infants over the first six months of life.
Acta Paediatr
April 1992
Department of Pediatrics, University of Pavia, Italy.
In the present study salivary IgA, anti-Escherichia coli, anti-beta-lactoglobulin and anti-poliovirus type 1 IgA and IgM in serum and saliva were evaluated longitudinally in 13 breast-fed and 14 formula-fed infants over the first six months of life. Salivary IgA was quantified by electroimmunodiffusion; specific IgA and IgM antibodies were determined in serum and saliva by ELISA. Salivary IgA was significantly lower at age one month in breast-fed compared with formula-fed infants but in breast-fed infants salivary IgA increased with age and was significantly higher at six months than at one month.
View Article and Find Full Text PDFSecretory IgA and serum type IgA in nasal secretion and antibody activity against the M protein.
Ann Otol Rhinol Laryngol
September 1987
We studied IgA immunoglobulins in nasal secretions in order to clarify mucosal immunity of the nasal cavity and paranasal sinuses during chronic nasal infection. Secretory IgA and serum type IgA of 165 samples of nasal secretions were analyzed quantitatively by use of electroimmunodiffusion techniques, and the specific antibody activity of secretory IgA against the M protein of Streptococcus pyogenes was investigated by use of enzyme-linked immunosorbent assay. Results show that although the secretory IgA content in nasal secretions was elevated in chronic sinusitis, its specific antibody activity against the M protein was lower than that in normal subjects.
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