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Sacubitril/valsartan is associated with improvements in quality of life in adult congenital heart disease patients with systemic right ventricular failure.
Open Heart
January 2025
Center for Congenital Heart Disease Amsterdam Leiden (CAHAL), Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands
Background: Short-term improvements in quality of life (QOL) have been reported in adult congenital heart disease patients with systemic right ventricle (sRV) failure after treatment with sacubitril/valsartan. This study aimed to evaluate the medium-term QOL changes in sRV failure patients treated with sacubitril/valsartan.
Methods: In this single-centre, prospective cohort study, patients with symptomatic sRV failure completed the Netherlands Organisation for Applied Scientific Research/Academic Hospital Leiden Questionnaire for Adult's Health-Related Quality of Life (TAAQOL) at baseline and after starting treatment with sacubitril/valsartan.
Effects of Hydration and a Hyaluronic Acid-Containing Lozenge on Voice Parameters in Conjunction With a Vocal Loading Test.
J Speech Lang Hear Res
January 2025
Division of Phoniatrics and Pediatric Audiology, Department of Otolaryngology, Munich University Hospital and Faculty of Medicine, Munich University (Ludwig-Maximilians-Universität), Germany.
Purpose: This study explores the effects of water intake and a hyaluronic acid (HA)-containing lozenge on acoustic measurements and vocal oscillation patterns investigated after a vocal loading test (VLT).
Method: Ten healthy subjects (five females, five males) read out loud a standardized text for 10 min at a target level of 80 dB(A), measured 30 cm from the mouth, under three conditions but each after fasting for 2 hr: (a) drinking 0.7 l of water, (b) sucking an HA-containing lozenge, and (c) neither of both before the VLT.
Worth your sweat: wearable microfluidic flow rate sensors for meaningful sweat analytics.
Lab Chip
January 2025
Antwerp Engineering, Photoelectrochemistry and Sensing (A-PECS), University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Wearable microfluidic sweat sensors could play a major role in the future of monitoring health and wellbeing. Sweat contains biomarkers to monitor health and hydration status, and it can provide information on drug intake, making it an interesting non-invasive alternative to blood. However, sweat is not created in excess, and this requires smart sweat collection strategies to handle small volumes.
View Article and Find Full Text PDFHeat-health messaging in Canada: A review and content analysis of public health authority webpages and resources.
Public Health Pract (Oxf)
June 2025
Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, ON, Canada.
Background: With the growing threat posed by extreme heat, heat-health messaging communicated by public health authorities is critical for raising community awareness and action. This study sought to (i) identify what heat-health content is shared online by Canadian public health authorities and (ii) analyse the material to develop an understanding of the content included within the resources.
Study Design: Qualitative content analysis.
Relationship between fluid intake, hydration status and cortisol dynamics in healthy, young adult males.
Compr Psychoneuroendocrinol
February 2025
Department of Kinesiology, University of North Carolina at Greensboro, Greensboro, Mailing address: P.O. Box 26170 Greensboro, NC, 27402-6170, USA.
Background: Previous studies have identified links between fluid intake, hydration related hormones and cortisol measured at one timepoint but have not considered how hydration may influence cortisol dynamics throughout the day. This study assessed associations between hydration status (copeptin, urinary osmolality, urine volume) and habitual fluid intake with cortisol dynamics.
Methods: The day before (DB) a 6-h laboratory visit, 29 male participants (age, 23±4y; BMI, 25.
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