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Visibility of Intracranial Perforating Arteries Using Ultra-High-Resolution Photon-Counting Detector Computed Tomography (CT) Angiography.
Tomography
November 2024
Department of Diagnostic Radiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara 259-1193, Japan.
Photon-counting detector computed tomography (PCD-CT) offers energy-resolved CT data with enhanced resolution, reduced electronic noise, and improved tissue contrast. This study aimed to evaluate the visibility of intracranial perforating arteries on ultra-high-resolution (UHR) CT angiography (CTA) on PCD-CT. A retrospective analysis of intracranial UHR PCD-CTA was performed for 30 patients.
View Article and Find Full Text PDFEffect of insulin on indices of cerebral blood flow and cerebrovascular compliance in young adults.
Am J Physiol Heart Circ Physiol
January 2025
Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, United States.
Insulin has important vasodilatory effects in the peripheral circulation, but less is known about insulin's role in cerebrovascular control. Herein, we hypothesized both systemic (intravenous) and local (intranasal) insulin administration would increase indices of cerebral blood flow and reduce cerebrovascular compliance (Ci) in young adults. Participants were assigned to one of four separate protocols.
View Article and Find Full Text PDFFast Competitive Swimmers Demonstrate a Diminished Diving Reflex.
Scand J Med Sci Sports
October 2024
Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.
Competitive swimmers complete 50-m front crawl swimming without breathing or with a limited number of breaths. Breath holding during exercise can trigger diving reflex including bradycardia and diminished active muscle blood flow, whereas oxygen supply to vital organ such as brain is maintained. We hypothesized that swimmers achieving faster time in 50-m front crawl with limited number of breaths demonstrate a blunted diving reflex of cardiac and active muscle blood flow responses with elevated cerebral perfusion to counteract peripheral and central fatigues.
View Article and Find Full Text PDFBiomarkers of mitochondrial stress and DNA damage during pediatric catheter-directed neuroangiography - a prospective single-center study.
Pediatr Radiol
October 2024
Program in Molecular Medicine, SickKids Research Institute, Toronto, ON, Canada.
Background: Neuroangiography represents a critical diagnostic and therapeutic imaging modality whose associated radiation may be of concern in children. The availability of in vivo radiation damage markers would represent a key advancement for understanding radiation effects and aid in the development of radioprotective strategies.
Objective: Determine if biomarkers of cellular damage can be detected in the peripheral blood mononuclear cells (PBMC) of children undergoing neuroangiography.
The complexity of cerebral blood flow regulation: the interaction of posture and vasomotor reactivity.
J Appl Physiol (1985)
October 2024
Cerebral Haemodynamics in Ageing and Stroke Medicine (CHiASM) Research Group, Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Arterial carbon dioxide ([Formula: see text]) and posture influence the middle (MCAv) and posterior (PCAv) cerebral artery blood velocities, but there is paucity of data about their interaction and need for an integrated model of their effects, including dynamic cerebral autoregulation (dCA). In 22 participants (11 males, age 30.2 ± 14.
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