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Feasibility and impact of sentinel lymph node biopsy in patients affected by ano-rectal melanoma.
Tech Coloproctol
January 2025
Department of Surgical Sciences, University of Turin, Turin, Italy.
Introduction: Anorectal melanoma (ARM) is rare and highly lethal neoplasm. It has a poorer prognosis compared with cutaneous ones. Sentinel lymph node biopsy (SLNB) has become the preferred method of nodal staging method for cutaneous melanoma.
View Article and Find Full Text PDFReversal of Basal Ganglia Hypermetabolism Following Surgical Removal of Adrenocorticotropic Hormone-Producing Lung Carcinoid in a Patient of Cushing Syndrome With Unusual Presentation of Acute Psychosis: Proof of Concept.
Clin Nucl Med
December 2024
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, India.
Article Synopsis
- A 34-year-old woman diagnosed with severe psychosis also showed signs of Cushing syndrome and underwent an 18 F-FDG PET/CT scan, which identified a hypermetabolic lung lesion and increased brain metabolism in the basal ganglia.
- The lung lesion was surgically removed and confirmed as an adrenocorticotropic hormone-producing lung carcinoid through histopathological analysis.
- After treatment, a follow-up 18 F-FDG PET scan revealed normal brain metabolism and a complete reversal of the psychosis, highlighting the potential for psychosis to be an initial symptom of Cushing syndrome and the usefulness of PET imaging in assessing brain changes.
Role of Interstitial Cells of Cajal in Congenital Ureteropelvic Junction Obstruction.
Afr J Paediatr Surg
September 2024
Department of Pathology, Bhima Bhoi Medical College and Hospital, Bolangir, Odisha, India.
Background: Although congenital ureteropelvic junction (UPJ) obstruction is the most common cause of neonatal hydronephrosis, aetiopathogenesis is still inconclusive. Recently, the paucity of interstitial cells of Cajal (ICC) at the narrow adynamic part of UPJ has been implicated as a causative factor.
Materials And Methods: This prospective study was conducted between October 2019 and March 2022 to find out the density of ICC by the immunohistochemical method using CD117 (c-kit) antibody, in resected segments of UPJ in obstruction patients and in renal tumour patients as control.
Multiple Synchronous Thoracoabdominal Duplication Cysts With Ectopic Gastric Mucosa Detected on 99mTc-Pertechnetate Scintigraphy and SPECT/CT.
Clin Nucl Med
October 2024
From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Thoracoabdominal duplication cysts are a congenital malformation of the posterior primitive foregut with synchronous thoracic and abdominal duplication cysts being found in up to 15% of cases. The presentation of duplication cysts depends on their location, size, and other factors, like the presence of ectopic functioning gastric mucosa, which is reported in 20%-30% of duplication cysts. 99mTc-pertechnetate scintigraphy along with SPECT/CT helps in the preoperative localization of ectopic functioning gastric mucosa in these duplication cysts.
View Article and Find Full Text PDFAn Incidental Detection of Breast Cancer Osteolytic Bone Metastasis Using a 99m Tc-TRODAT-1 SPECT Scan.
Clin Nucl Med
November 2024
From the Department of Nuclear Medicine, Hsinchu Mackay Memorial Hospital, Hsinchu, Taiwan.
This report presents a case of suspected Parkinson disease in a 76-year-old woman with a history of slurred speech, general weakness, unstable gait, and bradykinesia for months. A 99m Tc-TRODAT-1 SPECT scan revealed a symmetrically decreased bilateral nigrostriatal system, including bilateral putamen and caudate nuclei. The scintigraphic findings may reflect normal aging or atypical parkinsonism.
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