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Current Clinical Practice Guidelines for Nutritional Screening Before and After Sleeve Gastrectomy and Roux-En-Y Gastric Bypass: A Scoping Review.
Curr Obes Rep
January 2025
Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, University of Leuven, Herestraat 49 - Box 7003, 3000, Leuven, Belgium.
Introduction: Long-term data indicate that patients who underwent metabolic bariatric surgery have a higher risk of developing nutritional complications. Therefore, it is of utmost importance to monitor their nutritional status.
Methods: A scoping literature search was conducted in MEDLINE, EMBASE, CINAHL, and TRIP database to identify clinical practice guidelines for nutritional screening before and after metabolic bariatric surgery from learned societies.
[Current state of patient knowledge regarding the preoperative impact and causes of anemia].
Anaesthesiologie
January 2025
Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Frankfurt, Frankfurt, Deutschland.
Background: Despite being treatable, the prevalence of anemia is relatively high, affecting up to 30% of the general population and 35% of patients undergoing surgery. Symptoms are often misinterpreted and patients frequently do not recognize anemia as a disease. As a result, it is often not discussed during medical consultations.
View Article and Find Full Text PDFMultiple-Dose Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Subcutaneous Rusfertide, a Hepcidin Mimetic, in Healthy Subjects.
Clin Pharmacol Drug Dev
January 2025
Protagonist Therapeutics, Inc., Newark, CA, USA.
Rusfertide, a peptide hepcidin mimetic, has shown efficacy in polycythemia vera. This trial investigated the multiple-dose pharmacokinetics, pharmacodynamics, and safety of once-weekly rusfertide 60 mg for 5 weeks in healthy subjects. Subjects were randomized to subcutaneous injection in the abdomen, upper arm, or thigh.
View Article and Find Full Text PDFPrevalence and Treatment Patterns of Anaemia in Individuals With Chronic Kidney Disease Across Asia: A Systematic Review and Meta-Analysis.
Nephrology (Carlton)
February 2025
The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Aim: Anaemia is a significant complication of chronic kidney disease (CKD). However, its prevalence and treatment patterns in Asia are poorly understood. We sought to quantify prevalence of anaemia and its treatment in people with CKD across the region.
View Article and Find Full Text PDFManaging Doxorubicin Cardiotoxicity: Insights Into Molecular Mechanisms and Protective Strategies.
J Biochem Mol Toxicol
February 2025
College of Medicine, Al-Ayen Iraqi University, An Nasiriyah, Iraq.
Cancer ranks as the second leading cause of death in the United States and poses a significant health challenge globally. Numerous therapeutic options exist for treating cancer, with chemotherapy being one of the most prominent. Chemotherapy involves the use of antineoplastic drugs, either alone or in combination with other medications, to target and kill cancer cells.
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