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N1 derived lipoteichoic acid alleviates insulin resistance in association with modulation of the gut microbiota and amino acid metabolism.
Food Funct
January 2025
College of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310014, China.
This study aimed to investigate the effects of heat-killed N1 (HK-N1) and lipoteichoic acid (LTA) derived from it on alleviating insulin resistance by modulating the gut microbiota and amino acid metabolism. High-fat diet (HFD)-fed mice were administered live bacteria or HK-N1, and the results demonstrated that HK-N1 significantly reduced epididymal adipocyte size and serum low density lipoprotein-cholesterol, and improved insulin resistance by increasing the YY peptide and glucagon-like peptide levels. HK-N1 also modulated the gut microbiome composition, enhancing microbiota uniformity and reducing the abundance of , and .
View Article and Find Full Text PDFNon-high-density to high-density lipoprotein cholesterol ratio and its association with infertility in U.S. women: a cross-sectional study.
Front Endocrinol (Lausanne)
January 2025
Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Objective: To investigate the relationship between Non-High-Density Lipoprotein Cholesterol to High-Density Lipoprotein Cholesterol Ratio (NHHR) and infertility in US female adults aged 20 to 45.
Methods: Our research team utilized data from the 2013-2018 National Health and Nutrition Examination Survey (NHANES) to conduct a cross-sectional study. Multivariable logistic regression was conducted to examine the association between NHHR and infertility, with trend tests providing additional insight into this relationship.
Serum lipid profile in systemic lupus erythematosus.
Front Immunol
January 2025
Department of Rheumatology and Clinical Immunology, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Background: Dyslipidemia presents in various autoimmune diseases, and the serum lipid profile in systemic lupus erythematosus (SLE) has not yet been clearly defined. This study aims to evaluate the level of serum lipids in patients with SLE.
Methods: A case-control study evaluated four conventional sera lipids-total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL)-in patients with SLE compared to healthy controls (HCs).
Goal attainment, medication adherence and guideline adherence in the treatment of hypertension and dyslipidemia in Irish populations: A systematic review and meta-analysis.
Int J Cardiol Cardiovasc Risk Prev
March 2025
Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Cork, Ireland.
Background: The appropriate treatment high blood pressure (BP) and low-density lipoprotein cholesterol.(LDL-C), according to clinical guidelines, reduces a patient's risk of a cardiovascular event.
Aim: This systematic review aims to evaluate the attainment of BP and LDL-C goals among the Irish population in both primary and secondary prevention of cardiovascular diseases, the level of adherence to prescribing guidelines by doctors and the level of medication adherence among patients.
The correlation between insulin resistance and blood lipids in children.
J Med Biochem
November 2024
WuXi Children's Hospital, Department of Endocrine, Wuxi, Jiangsu Province, China.
Background: This work focused on the correlation between insulin resistance (IR) and blood lipids (BL) in children with simple obesity, as well as the intervention effects of high-intensity interval training (HIIT) in weight loss in children.
Methods: 80 children aged 6 to 17 years with simple obesity were selected from our hospital and randomly grouped into two groups. Children in the control (Ctrl) group underwent traditional moderate-intensity continuous training (MICT), while those in the other group received HIIT (HIIT group).
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