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Hypersensitivity pneumonitis (HP), including pigeon breeder's lung (PBL), often progresses from acute inflammation to fibrosis, impairing lung function and limiting targeted therapeutic strategies. Mechanistic studies on PBL progression are limited by the lack of preclinical animal models and a predominant focus on patient data. This study explores the immunopathological characteristics of all stages of PBL in mice and evaluates the therapeutic potential of human umbilical cord-derived mesenchymal stem cells (UC-MSCs) during the non-fibrotic stage.

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Aerodynamic analysis of complex flapping motions based on free-flight biological data.

Bioinspir Biomim

January 2025

Intelligent Robotics Institute, School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, People's Republic of China.

The wings of birds contain complex morphing mechanisms that enable them to perform remarkable aerial maneuvers. Wing morphing is often described using five wingbeat motion parameters: flapping, bending, folding, sweeping, and twisting. However, the specific impact of these motions on the aerodynamic performance of wings throughout the wingbeat cycle, and their potential to inform engineering applications, remains insufficiently explored.

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Cyanobacteria hot spot detection integrating remote sensing data with convolutional and Kolmogorov-Arnold networks.

Sci Total Environ

January 2025

Interdisciplinary Lab for Mathematical Ecology and Epidemiology & Department of Mathematical and Statistical Sciences, University of Alberta, Canada. Electronic address:

Prompt and accurate monitoring of cyanobacterial blooms is essential for public health management and understanding aquatic ecosystem dynamics. Remote sensing, in particular satellite observations, presents a good alternative for continuous monitoring. This study employs multispectral images from the Sentinel-2 constellation alongside ERA5-Land to enable broad-scale data acquisition.

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Visualized neural network-based vibration control for pigeon-like flexible flapping wings.

ISA Trans

January 2025

School of Artificial Intelligence, Anhui University, Hefei 230601, China. Electronic address:

This study investigates pigeon-like flexible flapping wings, which are known for their low energy consumption, high flexibility, and lightweight design. However, such flexible flapping wing systems are prone to deformation and vibration during flight, leading to performance degradation. It is thus necessary to design a control method to effectively manage the vibration of flexible wings.

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Near telomere-to-telomere assembly of the Tarim pigeon (Columba livia) genome.

Sci Data

December 2024

Department of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China.

Pigeons serve as important model animals and commercial poultry. The Tarim pigeon, as a breed of Columba livia, is a locally indigenous breed unique to China. While the genome of C.

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