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Identification of broadly-conserved parasitic nematode proteins that activate immunity.
Front Parasitol
August 2023
Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States.
Introduction: Soil transmitted nematodes are impediments to human health and agricultural production. Poor anthelmintic efficiencies, the emergence of resistant strains, and the persistence of infective stages highlight the need for more effective control strategies. Parasitic nematodes elicit a Th2-type immune response that most often is not protective.
View Article and Find Full Text PDFAntiparasitic activity of the iron-containing milk protein lactoferrin and its potential derivatives against human intestinal and blood parasites.
Front Parasitol
February 2024
Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, United States.
An iron-containing milk protein named lactoferrin (Lf) has demonstrated antiparasitic and immunomodulatory properties against a variety of human parasites. This protein has shown its capability to bind and transport iron molecules in the vicinity of the host-pathogen environment. The ability of parasites to sequester the iron molecule and to increase their pathogenicity and survival depends on the availability of iron sources.
View Article and Find Full Text PDFA brief insight into species - a growing threat to public health.
Front Antibiot
December 2023
Department of Biochemistry & Microbiology, North South University, Dhaka, Bangladesh.
spp. are Gram-negative, non-spore forming, rod-shaped, facultative anaerobic bacteria from the family often found in soil, sewage, sludge, water, food, and the intestinal tracts of animals and humans. Several members of spp.
View Article and Find Full Text PDFUtilization of mannan oligosaccharides as antibiotic substitutes in laying hens.
Vet Res Forum
December 2024
Department of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.
Among global concerns about antibiotic resistance, it is necessary to identify food-safe alternatives to enhance production. This study aimed to evaluate the impact of mannan oligosaccharides (MOS) inclusion to replace antibiotic growth promoters (AGP) in the diets of ISA Brown laying hens aged between 23 and 31 weeks. Two hundred forty hens were grouped into five treatments: Control, AGP (130 ppm of enramycin 8.
View Article and Find Full Text PDFNewly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium.
Vet Res
January 2025
National and Regional Joint Engineering Laboratory for Medicament of Zoonoses Prevention and Control, Key Laboratory of Zoonoses, Ministry of Agriculture, Key Laboratory of Zoonoses Prevention and Control of Guangdong Province, Key Laboratory of Animal Vaccine Development, Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
S. Typhimurium is a significant zoonotic pathogen, and its survival and transmission rely on stress resistance and virulence factors. Therefore, identifying key regulatory elements is crucial for preventing and controlling S.
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