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Transitioning from perceived stress to mental health: The mediating role of self-control in a longitudinal investigation with MRI scans.
Int J Clin Health Psychol
January 2025
Faculty of Psychology, MOE Key Laboratory of Cognition and Personality, Southwest University, Chongqing, 400715 China.
Background: The neural mechanisms and long-term effects of perceived stress (PS) and self-control (SC) on mental health (MH) are not fully understood. This study seeks to investigate the influence of PS and SC on MH and to identify their neural correlates using fMRI.
Methods: A total of 817 college students participated in behavioral assessments, including the Perceived Stress Scale (PSS), Self-Control Scale (SCS), and Mental Health Continuum Short Form (MHC-SF).
Dissociable ventral and dorsal sensorimotor functional circuits linking the hypomanic personality traits to aggression via behavioral inhibition system.
Int J Clin Health Psychol
January 2025
Faculty of Psychology, Tianjin Normal University, Tianjin, 300387, China.
Hypomanic personality traits (HPT) are susceptibility markers for psychiatric disorders, particularly bipolar disorder, and are strongly associated with aggressive behaviors. However, the neuropsychological mechanisms underlying this association remain unclear. This study utilized psychometric network analysis and (IS-RSA) to explore the neuropsychological circuits that link HPT to aggression in a large non-clinical population.
View Article and Find Full Text PDFFunctional expression of Cry proteins on the surface of spores.
J Pestic Sci
November 2024
Bacillus Tech LLC.
The Cry1Fa insecticidal protein from (Bt) was expressed on the surface of (Bs) spores to create transgenic Bs spores referred to as Spore-Cry1Fa. Cry1Fa, along with its leader sequence, was connected to the carboxyl end of a Bs spore outercoat protein, CotC, through a flexible linker. The Arg-27 residue of the Cry1Fa protein was mutated to Leu to prevent detachment from the spores due to protease digestion.
View Article and Find Full Text PDFType 3 deiodinase activation mediated by the Shh/Gli1 axis promotes sepsis-induced metabolic dysregulation in skeletal muscles.
Burns Trauma
January 2025
Department of Critical Care Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, No. 321 Zhongshan Road, Gulou District, Nanjing, Jiangsu 210008, China.
Background: Non-thyroidal illness syndrome is commonly observed in critically ill patients, characterized by the inactivation of systemic thyroid hormones (TH), which aggravates metabolic dysfunction. Recent evidence indicates that enhanced TH inactivation is mediated by the reactivation of type 3 deiodinase (Dio3) at the tissue level, culminating in a perturbed local metabolic equilibrium. This study assessed whether targeted inhibition of Dio3 can maintain tissue metabolic homeostasis under septic conditions and explored the mechanism behind Dio3 reactivation.
View Article and Find Full Text PDFE74-like ETS transcription factor 3 expression and regulation in human intervertebral disc.
JOR Spine
March 2025
SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), The NEIRID Group (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases) Santiago University Clinical Hospital Santiago de Compostela Spain.
Background: Intervertebral disc degeneration (IVDD) is one of the main causes of chronic low back pain. The degenerative process is often initiated by an imbalance between catabolic and anabolic pathways. Despite the large socio-economic impact, the initiation and progress of disc degeneration are poorly understood.
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