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First report of anthelmintic resistance among sheep in six farms from three governorates in Jordan.
Vet Parasitol Reg Stud Reports
January 2025
Department of Basic Medical Veterinary Sciences, Jordan University of Science & Technology, Irbid, Jordan.
This study aimed to identify the presence of gastrointestinal nematode populations resistant to albendazole, levamisole, and ivermectin in six farms located in three regions of Jordan (Irbid, Mafraq, and Ma'an). Infected sheep (40 per farm) with at least 100 eggs per gram were randomly divided into four groups (10 animals per group). Three groups were treated with ivermectin, albendazole, or levamisole while the fourth group was used as a negative control group.
View Article and Find Full Text PDFDrug combination assays using Caenorhabditis elegans as a model system.
J Pharmacol Toxicol Methods
January 2025
Instituto de Investigaciones Bioquímicas de Bahía Blanca, Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS)-CONICET, 8000 Bahía Blanca, Argentina.
The C. elegans drug combination assay evaluates the effects of drug combinations in the nematode Caenorhabditis elegans, serving as a valuable tool to assess the efficacy of pharmaceutical agents and natural compounds. Using C.
View Article and Find Full Text PDFLevamisole, as a viral vaccine adjuvant, induces robust host defense through the modulation of innate and adaptive immune responses.
Front Microbiol
January 2025
Center for Foot-and-Mouth Disease Vaccine Research, Animal and Plant Quarantine Agency, Gimcheon-si, Republic of Korea.
Introduction: An effective vaccination policy must be implemented to prevent foot-and-mouth disease (FMD). However, the currently used vaccines for FMD have several limitations, including induction of humoral rather than cellular immune responses.
Methods: To overcome these shortcomings, we assessed the efficacy of levamisole, a small-molecule immunomodulator, as an adjuvant for the FMD vaccine.
Spatial occurrence of emerging contaminants in rivers and wastewater. Analysis of environmental and human risks.
Environ Toxicol Chem
January 2025
Laboratorio de Desarrollo Analítico y Quimiometría (LADAQ), Cátedra de Química Analítica I, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral (UNL), Santa Fe, Argentina.
This study assesses the occurrence of emerging contaminants (ECs) from agricultural and livestock production activities along the Salado River (Santa Fe province, Argentina). Of the 23 ECs studied, 8 were detected and quantified in river and wastewater samples, including ciprofloxacin, enrofloxacin, chlorpyrifos-methyl, albendazole, fenbendazole, levamisole, diazepam, and thiamethoxam. In river samples, the highest concentrations corresponded to ciprofloxacin, chlorpyrifos-methyl, and enrofloxacin.
View Article and Find Full Text PDFMagnetic particles (FeO) magnify ion transfer processes at the electrified liquid-liquid interface. Case study: Levamisole detection.
Talanta
December 2024
University of Lodz, Department of Inorganic and Analytical Chemistry, Electroanalysis and Electrochemistry Group, Faculty of Chemistry, Tamka 12, 91-403, Lodz, Poland. Electronic address:
This article describes the effect of non-stabilized magnetic particles FeO (nanoparticles aggregates) addition to the aqueous phase of the polarized liquid-liquid interface (LLI) on the interfacial ion transfer processes. LLI was formed between 1,2-dichloroethane and water solutions (1,2 DCE)|water. The synthesis of FeO magnetic particles (MPs) was achieved by the co-precipitation method, after which their appearance, size of aggregates, and zeta potential were assessed.
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