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Europe previously approved tecovirimat for mpox, based on animal data; the U.S. has stockpiled it for smallpox.
View Article and Find Full Text PDFMonkeypox-related knowledge and vaccination willingness among HIV-diagnosed and -suspected males: a cross-sectional survey in Changsha.
Front Public Health
January 2025
Changsha Centre for Disease Control and Prevention, Changsha, Hunan, China.
Objective: This study aimed to update baseline data on monkeypox (mpox)-related knowledge and vaccination willingness among human immunodeficiency virus (HIV) diagnosed and suspected males.
Methods: The cross-sectional survey was conducted in Changsha, a provincial capital in China, during 5 JULY to 5 SEPTEMBER 2023. Among the three study groups, the participants in the "previously diagnosed" group were recruited from a cohort of HIV-infected patients.
"If that would have lessened my symptoms, that would have been great...": a qualitative study about the acceptability of tecovirimat as treatment for mpox.
BMC Med
January 2025
Health Emergencies Programme, World Health Organization, Geneva, Switzerland.
Background: Tecovirimat, an antiviral treatment for smallpox, was approved as a treatment for mpox by the European Medicines Agency in January 2022. Approval was granted under "exceptional circumstances" based on effectiveness found in pre-clinical challenge studies in animals and safety studies in humans showing minimal side effects. As clinical efficacy studies are still ongoing, there is currently limited information with regard to the acceptability of tecovirimat to treat mpox.
View Article and Find Full Text PDFImmunobiology of MPox Infection and Its Management: Experience From Developing Nations.
Rev Med Virol
January 2025
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Purpose: As humanity grapples with the COVID-19 pandemic caused by the novel SARS-CoV-2 virus, the rising threats of the MPox virus (MPXV) in 2022 and 2024 have shown signs of global transmission and the potential to spark another pandemic. Though MPXV has been present for over 5 decades, with cases traditionally confined to endemic regions in West and Central Africa, recent outbreaks have occurred in multiple non-endemic regions, declaring itself as a Public Health Emergency of International Concern. This study aims to examine the patterns of MPXV transmission, its zoonotic potential, associated complications, and viable strategies to control its spread.
View Article and Find Full Text PDFOrf Infection (Ecthyma Contagiosum) Transmitted from Sheep to Child: A Case Report.
S D Med
October 2024
University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Orf is a parapoxvirus endemically found in sheep and goats. Orf can be transmitted to humans in close contact with infected animals, causing a self-limited viral skin infection known as ecythyma contagiosum. The diagnosis can be made clinically and treatment is usually conservative; however, unfamiliarity with orf may lead to an extended work-up.
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