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[Adenoid cystic carcinoma of the maxillary sinus and lateral skull base was removed and the submental artery island flap repaired the hard palate: a case report].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
Article Synopsis
- Adenoid cystic carcinoma is a malignant tumor located in the head and neck region, specifically affecting the skull base in this case.
- The tumor significantly involved various anatomical areas, including the sphenoid sinus and pterygopalatine fossa.
- The treatment involved surgery for removal, reconstruction of the site, and postoperative radiotherapy, leading to a positive outcome for the patient.
TRPS1 expression in cytologic specimens of salivary duct carcinoma and other salivary gland tumors.
Ann Diagn Pathol
February 2025
Department of Pathology, Albany Medical Center, Albany Medical College, Albany, NY, USA.
Recent studies suggest that trichorhinophalangeal syndrome type 1 (TRPS1) is sensitive immunomarker for breast carcinoma (BC). Salivary duct carcinoma (SDC) of salivary gland can share similar morphologic and immunophenotypic features with BC. This study aimed to assess the expression of TRPS1 in SDC and other salivary gland tumors (SGTs).
View Article and Find Full Text PDFSurvival benefit added by adjuvant chemotherapy in adenoid cystic carcinoma of salivary gland.
Sci Rep
October 2024
Department of Radiotherapy, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, 450008, PR China.
The aim of this study was to investigate the potential survival advantages associated with chemoradiotherapy (CRT) compared to radiotherapy (RT) as standalone modalities in the treatment of adenoid cystic carcinoma (ACC) of the salivary glands. Patients diagnosed with resected salivary gland ACC were retrospectively enrolled and categorized into two groups based on the type of adjuvant therapy received. The overall survival outcomes between the CRT and RT cohorts were evaluated using a multivariable Cox model.
View Article and Find Full Text PDFManaging malignant sublingual gland tumors: a single institution experience with 23 patients.
BMC Cancer
September 2024
Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan City, 430079, China.
Article Synopsis
- Malignant tumors of the sublingual gland are rare and challenging to diagnose and treat, highlighting the need for better understanding of their pathology, characteristics, and management strategies.
- This study reviewed 23 cases of sublingual gland malignancies, identifying adenoid cystic carcinoma and mucoepidermoid carcinoma as the most common types and emphasizing the importance of early diagnosis and surgical intervention for favorable outcomes.
- Surgical excision is the primary treatment approach, often accompanied by radiotherapy for advanced cases, and reconstruction techniques are employed to address significant tissue defects in the mouth.
Immunohistochemical expression of the cation channel TRPC6 in the submandibular and lacrimal gland and in salivary gland tumors.
Pathol Res Pract
September 2024
Institute for Anatomy and Cell Biology, Saarland University, Homburg 66421, Germany. Electronic address:
Background: Canonical transient receptor potential channels play a crucial role in cancer cell proliferation. While TRPC6 subtype detection in submandibular glands and the relevance of some TRPC channels in this gland have been shown in animal models, its histological detection in human lacrimal and submandibular glands, as well as related tumors, lacks systematic study. Studying TRPC6 in humans could lead to new therapeutic options.
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