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Readiness for Perception and Action: Towards a More Mechanistic Understanding of Phasic Alertness.

J Cogn

January 2025

Neuro-Cognitive Psychology, Department of Psychology, Bielefeld University, Bielefeld, Germany.

Human survival requires prompt perception and action to address relevant events in the environment. For this, the brain has evolved a system that uses warning stimuli to elicit phasic alertness, a state readying the brain for upcoming perception and action. Although a wealth of empirical evidence revealed how phasic alertness improves a wide range of perceptual and cognitive processing, it is still unclear by what cognitive mechanisms this is achieved.

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Unraveling the functional complexity of the locus coeruleus-norepinephrine system: insights from molecular anatomy to neurodynamic modeling.

Cogn Neurodyn

December 2025

The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Institute of Health and Rehabilitation Science, Xi'an Jiaotong University, Xi'an, 710049 Shaanxi China.

The locus coeruleus (LC), as the primary source of norepinephrine (NE) in the brain, is central to modulating cognitive and behavioral processes. This review synthesizes recent findings to provide a comprehensive understanding of the LC-NE system, highlighting its molecular diversity, neurophysiological properties, and role in various brain functions. We discuss the heterogeneity of LC neurons, their differential responses to sensory stimuli, and the impact of NE on cognitive processes such as attention and memory.

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Dysfunctional parenting (DP) is a factor of vulnerability and a predictive risk factor for psychopathology. Although previous research has shown specific functional and structural brain alterations, the neural basis of DP remains understudied. We therefore investigated EEG functional connectivity changes within the Salience Network before and after the exposure to attachment-related stimuli in individuals with high and low perceived DP.

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Neuroimaging features for cognitive fatigue and its recovery with VR intervention: An EEG microstates analysis.

Brain Res Bull

January 2025

Department of Radiology, Functional and Molecular Imaging Key Lab of Shaanxi Province, The Second Affiliated Hospital of Air Force Medical University, No.569 Xinsi Road, Xi'an, 710038, Shaanxi, China. Electronic address:

Introduction: Cognitive fatigue is mainly caused by enduring mental stress or monotonous work, impairing cognitive and physical performance. Natural scene exposure is a promising intervention for relieving cognitive fatigue, but the efficacy of virtual reality (VR) simulated natural scene exposure is unclear. We aimed to investigate the effect of VR natural scene on cognitive fatigue and further explored its underlying neurophysiological alterations with electroencephalogram (EEG) microstates analysis.

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Semantic memory, a repository for concepts and factual information, plays a vital role in acquiring and retrieving knowledge. This study explores the impact of age-related knowledge accumulation on semantic cognition, investigating whether a denser representational space affects retrieval processes. Using a semantic feature verification task, we employ both behavioral (reaction time; RT) and neurophysiological (event-related potential; ERP) measures to explore these dynamics across young and older adults.

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