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Impairment of Internal Auditory Canal Barrier in Meniere's Disease.
Clin Otolaryngol
October 2024
From the Department of Radiology, First Hospital of China Medical University, Shenyang, Liaoning, China.
Article Synopsis
- The study investigated how the signal intensity ratio (SIR) at the internal auditory canal (IAC) relates to hearing impairment in patients with Meniere's disease (MD).
- Fifty patients were given a 3D-FLAIR MRI after receiving a contrast agent, allowing for comparisons between the affected and unaffected sides of their IAC.
- Results showed that the SIR was significantly higher on the affected side and correlated positively with hearing thresholds across all frequencies, suggesting damage to the IAC barrier may influence hearing loss in MD patients.
A Pediatric Case of Cogan's Syndrome With Internal Otitis.
Cureus
August 2024
Department of Otolaryngology, St. Marianna University School of Medicine, Kawasaki, JPN.
Cogan's syndrome is characterized by ocular symptoms and auditory vestibular dysfunction. Auditory vestibular dysfunction in Cogan's syndrome is believed to be similar to Ménière's disease, but the cause is not known in detail. We present the case of a 10-year-old boy with Cogan's syndrome.
View Article and Find Full Text PDFIntratympanic Gentamicin Injection for Endolymphatic Hydrops After Cochlear Implantation.
J Int Adv Otol
March 2024
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Endolymphatic hydrops has been documented as a possible complication of cochlear implantation; however, few studies have addressed its treatment. We describe the first case ever reported of delayed endolymphatic hydrops after a cochlear implant successfully treated with intratympanic gentamicin injection. A detailed discussion of this case with a focus on its management and outcomes will be provided in comparison with literature data.
View Article and Find Full Text PDFComparing the Saccule-to-Utricle Ratio in Early- Versus Late-Stage Meniere's Disease Patients.
Laryngoscope
December 2024
Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Objective: To compare the saccule-to-utricle ratio in early- versus late-stage Meniere's disease (MD) patients based on magnetic resonance imaging (MRI) images.
Methods: In this retrospective study, we performed 3-dimensional real inversion recovery (3D-real IR) MRI 24 h after intratympanic gadolinium administration in unilateral MD patients at early-stage (n = 56) and late-stage (n = 70). Two radiologists independently graded endolymphatic hydrops (EH) and the saccule-to-utricle ratio inversion (SURI) was compared between the two groups.
Atrial Natriuretic Peptide Alleviates Motion Sickness Potentially through Regulating Endolymph Volume in the Inner Ear Increased by Arginine Vasopressin.
Neuroendocrinology
August 2024
Department of Nautical and Diving Medicine, Institute of Nautical Medicine, Institute of Special Environmental Medicine, Medical School, and Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.
Introduction: Dimenhydrinate and scopolamine are frequently used drugs, but they cause drowsiness and performance decrement. Therefore, it is crucial to find peripheral targets and develop new drugs without central side effects. This study aimed to investigate the anti-motion sickness action and inner ear-related mechanisms of atrial natriuretic peptide (ANP).
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