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Successful Multi-Modal Laser Intervention and Histopathological Evaluation of Multiple Glomangiomas.
Lasers Surg Med
January 2025
Department of Dermatology, Veterans Health Administration, San Antonio, Texas, USA.
Objectives: Glomangiomas are benign vascular malformations that exist within the spectrum of glomuvenous malformations which consist of varying amounts of glomus cells, vascular spaces, and smooth muscle. Glomangiomas are often treated due to associated pain, particularly when located on pressure areas such as the back or extensor surfaces, which can cause difficulty with certain activities and occupational functions. Histologically glomangiomas consist of prominent dilated vascular spaces lined by glomus cells typically situated in the deep-dermis to subcutaneous fat which limits treatment to modalities capable of reaching the depth of the tumor including excision, sclerotherapy, and laser therapy.
View Article and Find Full Text PDFRenal Juxtaglomerular Cell Tumors Exhibit Distinct Genomic and Epigenomic Features and Lack Recurrent Gene Fusions: Comprehensive Molecular Analysis of a Multi-institutional Series.
Am J Surg Pathol
December 2024
Department of Pathology, Indiana University School of Medicine, Indianapolis, IN.
Juxtaglomerular cell tumor (JxGCT) is a rare type of renal neoplasm demonstrating morphologic overlap with some mesenchymal tumors such as glomus tumor (GT) and solitary fibrous tumor (SFT). Its oncogenic drivers remain elusive, and only a few cases have been analyzed with modern molecular techniques. In prior studies, loss of chromosomes 9 and 11 appeared to be recurrent.
View Article and Find Full Text PDFA case report: Multiple synchronous pain full glomus tumors in adjacent fingers; a review of multiple glomus tumors.
Int J Surg Case Rep
January 2025
Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address:
Article Synopsis
- Glomus tumors (GTs) are rare tumors typically found under the nails and can appear as single or multiple lesions, sometimes linked to genetic issues.
- A case study describes a 37-year-old woman with pain in her fingers due to a suspected GT, which was resolved after surgery.
- It emphasizes that GT should be considered in the diagnosis of painful lesions, highlighting the importance of early detection and treatment to relieve chronic pain.
Benign Glomus Tumor of the Urinary Bladder: A Case Report and Literature Review.
Int J Surg Pathol
December 2024
Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Article Synopsis
- * Imaging tests revealed a significant mass in the left bladder and a nonfunctional right kidney, leading to surgical removal of both the kidney and part of the bladder.
- * The final diagnosis was a bladder glomus tumor, and the patient remains healthy with no signs of recurrence after 15 months, underscoring the need for urologists to consider glomus tumors in their diagnostic process.
Glomus Tumor of the Chest Wall With Metastases to Lung.
Cureus
September 2024
Department of Medical Oncology, Summa Health, Akron, USA.
Article Synopsis
- Glomus tumors are usually benign but can be rare and aggressive in some cases, like the one in a 67-year-old woman whose tumor metastasized to her lungs.
- The patient underwent neoadjuvant radiation followed by immunotherapy with pembrolizumab, leading to significant disease regression and resolution of lung nodules.
- The case highlights the potential for using radiation and immunotherapy to manage malignant glomus tumors, which are rare and have uncertain treatment protocols.
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