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Metastatic onset of prostate carcinoma: A clinical and pathological challenge.
Indian J Pathol Microbiol
July 2024
Department of Urology, "Pius Brinzeu" Emergency County Hospital, Timisoara, Romania.
Introduction: Prostate cancer is the second most common cancer, following lung cancer, and the fifth leading cause of cancer death in men worldwide. The onset of the disease, characterized by symptoms or changes caused by distant metastases, is rare and poses a challenge for clinicians and pathologists. We aimed to present a series of prostate carcinoma (PC) with unusual, histologically confirmed distant metastases (pM1) at the time of diagnosis, which raised suspicions of other types or origins of the primary tumor.
View Article and Find Full Text PDFThe research advances in Kirsten rat sarcoma viral oncogene homolog (KRAS)-related cancer during 2013 to 2022: a scientometric analysis.
Front Oncol
April 2024
Department of Thyroid, Breast and Hernia Surgery, General Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Introduction: Cancer represents a significant global public health concern. In recent years, the incidence of cancer has been on the rise worldwide due to various factors, including diet, environment, and an aging population. Simultaneously, advancements in tumor molecular biology and genomics have led to a shift from systemic chemotherapy focused on disease sites and morphopathology towards precise targeted therapy for driver gene mutations.
View Article and Find Full Text PDFTakayasu's Arteritis: A Special Case Report and Review of the Literature.
Medicina (Kaunas)
March 2024
1st Surgery Department-Cardiac Surgery, "Gr. T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.
: Takayasu's arteritis is a rare type of vasculitis with severe complications like stroke, ischemic heart disease, pulmonary hypertension, secondary hypertension, and aneurysms. Diagnosis is achieved using clinical and angiographic criteria. Treatment is medical and surgical, but unfortunately, the outcome is limited.
View Article and Find Full Text PDFHistopathological Lung Findings in COVID-19 B.1.617.2 SARS-CoV-2 Delta Variant.
J Pers Med
January 2023
Institute of Legal Medicine, 400006 Cluj-Napoca, Romania.
Background: The Delta variant (Pango lineage B.1.617.
View Article and Find Full Text PDFSARS-CoV-2 Infection: What Is Currently Known about Homocysteine Involvement?
Diagnostics (Basel)
December 2022
Department of Morpho-Functional Sciences (II), Discipline of Physiology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly throughout the world causing health, social and economic instability. The severity and prognosis of patients with SARS-CoV-2 infection are associated with the presence of comorbidities such as cardiovascular disease, hypertension, chronic lung disease, cerebrovascular disease, diabetes, chronic kidney disease, and malignancy. Thrombosis is one of the most serious complications that can occur in patients with COVID-19.
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