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Higher levels of plasmatic saturated fatty acid were significantly associated with liver fibrosis in HIV mono-infection: A case-control study.
Metabol Open
December 2024
Laboratório de Pesquisa Clínica em DST/AIDS (LAPCLIN-AIDS), Instituto Nacional de Infectologia Evandro Chagas - Fundação Oswaldo Cruz (INI-FIOCRUZ), 21040-360, Rio de Janeiro, Brazil.
Background: The relationship between plasmatic fatty acid (FA) composition and liver fibrosis remains scarce in people living with HIV/AIDS (PLWHA). We aimed to evaluate the association of plasmatic FAs and liver fibrosis in HIV mono-infected individuals.
Methods: This case-control study included PLWHA with liver fibrosis (cases) and randomly selected subjects without fibrosis (controls) from the PROSPEC-HIV study (NCT02542020).
Dietary Bovine Lactoferrin Reduces the Deleterious Effects of Lipopolysaccharide Injection on Mice Intestine.
Nutrients
November 2024
UMR-PNCA, Université Paris-Saclay, AgroParisTech, INRAE, 91120 Palaiseau, France.
Background/objectives: Injection of lipopolysaccharides (LPS) in experimental models induces a systemic inflammatory response that is associated with deleterious effects on intestinal morphology and physiology. In this study, we have studied in female mice the effects of dietary supplementation with bovine lactoferrin (bLF) given before intraperitoneal injection of LPS on jejunum and colon.
Methods: The first study evaluated the efficiency of different bLF and LPS concentrations to determine the optimal experimental conditions.
Impact of obesity on low density lipoprotein plasmatic levels 6 weeks after an acute coronary syndrome.
Cardiovasc Endocrinol Metab
March 2025
Departments of Endocrinology.
Introduction: Cardiovascular disease is the leading cause of death. One of the main factors is obesity, which is on the rise. LDL levels below 0.
View Article and Find Full Text PDFInter- and intraspecific blood-related biomarkers and chemical exposure in confined and free-living sea turtles.
Environ Res
January 2025
Institut de Ciències del Mar, CSIC, Psg. Marítim de La Barceloneta 37-49, 08003, Barcelona, Spain. Electronic address:
Article Synopsis
- - The global importance of recovery centers and head-start programs for sea turtles focuses on their roles in rescue and conservation, while also generating crucial health data for monitoring and research on these species.
- - This study evaluated non-invasive blood biomarkers and ecotoxicological impacts in both confined green sea turtles and free-living turtles from the Mexican Caribbean, highlighting significant health differences influenced by captivity.
- - Findings revealed concerning health indicators in confined green turtles, such as abnormal blood cells and elevated toxin levels, compared to wild counterparts, emphasizing the need for improved health monitoring and conservation policies.
Physiology, gene expression, and behavior as potential indicators of oxidative stress in piglets.
BMC Vet Res
October 2024
Department of Animal and Food Science, Universitat Autònoma de Barcelona, Edifici V, Travessera dels Turons, Cerdanyola del Valles, 08193, Spain.
The goal of the current study was to develop a pig model to investigate oxidative stress with a low negative impact on piglet welfare. Four independent trials (A, B, C, and D) were performed using a single intraperitoneal shot of lipopolysaccharide (LPS) as an immune challenge, aiming to assess the minimal LPS dose for piglets of different age to trigger a measurable acute oxidative stress response in healthy animals. In trial A, piglets received an LPS dose of 25 µg/KgBW at 41 days post-weaning (p.
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