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Impact of interaction between individual genomes and preeclampsia on the severity of autism spectrum disorder symptoms.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha 410008.
Objectives: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Prior research suggests that genetic susceptibility and environmental exposures, such as maternal preeclampsia (PE) during pregnancy, play key roles in ASD pathogenesis. However, the specific effects of the interaction between genetic and environmental factors on ASD phenotype severity remain unclear.
View Article and Find Full Text PDFLongitudinal analysis of the bidirectional relationship between screen time and sleep: Exploring the role of physical activity.
Sleep Med
December 2024
School of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, Australia.
Background: Excessive screen time and poor sleep duration have significant implications for children's health and well-being. Understanding the dynamic relationship between screen time and sleep duration, as well as the impact of physical activity in this relationship, is essential for promoting healthy behaviours. The aims of this study were to: 1) investigate the bidirectional relationship between screen time and sleep duration in children, and 2) explore the mediating role of physical activity in these associations.
View Article and Find Full Text PDFRelationship-Centered Care for Older Adults in Long-Term Care Homes: A Scoping Review.
J Appl Gerontol
January 2025
Department of Gerontology, Simon Fraser University, Vancouver, BC, Canada.
This scoping review, following Levac et al.'s methodology, examines the implementation and impact of relationship-centered care (RCC) in long-term care (LTC) settings for older adults. Peer-reviewed articles from AgeLine, CINAHL Complete, MEDLINE, PsycINFO, and Web of Science were included if published after 2000, involved older adults in LTC homes, focused on RCC, and conducted in Australia, Europe, New Zealand, or North America.
View Article and Find Full Text PDFIn search of lost time: Discrete- versus continuous-time models of working alliance and symptom severity.
J Consult Clin Psychol
January 2025
Department of Clinical Psychology and Psychotherapy, Osnabruck University.
Objective: The therapeutic alliance is one of the most stable predictors of symptom burden over the course of therapy. So far, this effect has only been examined on the basis of sessions. Continuous-time models (CTM) allow this relationship to be modeled as a continuous process in which the actual time interval between measurements is considered.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Washington University in St. Louis, Saint Louis, MO, USA.
Background: Alzheimer disease (AD) is a chronic progressive neurodegenerative disorder that presents with cognitive dysfunction, memory loss, language difficulties, emotion dysregulation, and the eventual loss of motor function and death. Magnetic resonance imaging (MRI) shows early atrophy in the medial temporal lobes, which then spreads to the posterior temporal lobe, parietal lobe, and finally the frontal lobe with relative sparing of the sensorimotor cortex. Social disadvantage has been shown to have potentially additive impacts on aging trajectories.
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