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Newcastle Disease Vaccination Program in Broilers Using an Apathogenic Heat-Resistant Vaccine.
Arch Razi Inst
June 2024
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Newcastle disease (ND) is among the most common and deadliest poultry diseases worldwide. Thermostable Newcastle disease virus (NDV) vaccines have been widely used to protect village chickens against ND due to their decreased dependence on cold chains for transport and storage. The NDV4 Heat-Resistant (NDV4HR) vaccine is an apathogenic, heat-resistant, live vaccine that can induce immunity in chickens.
View Article and Find Full Text PDFImmunogenicity of Inactivated H5 Avian Influenza Vaccine Used in Commercial Laying Pullet in Tehran Province, Iran.
Arch Razi Inst
June 2024
Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Highly pathogenic avian influenza (HPAI) is a viral disease caused by some H5 and H7 subtypes of influenza virus type A in most species of birds, especially poultry. HPAI viruses are among the most challenging viruses that threaten both human and animal health. Consequently, various strategies, such as the use of vaccines have been proposed to control the disease.
View Article and Find Full Text PDFEnhancing antibody levels and T cell activity of quadrivalent influenza vaccine by combining it with CpG HP021.
Sci Rep
December 2024
State Key Laboratory for Diagnosis, Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China.
Influenza virus infections are a serious danger to people's health worldwide as they are responsible for seasonal flu outbreaks. There is an urgent need to improve the effectiveness and durability longevity of the immune response to influenza vaccines. We synthesized the CpG HP021 and examined the impact of it on the immune response to an influenza vaccine.
View Article and Find Full Text PDFImmunogenicity and safety of live attenuated influenza vaccine in children aged 3-17 years in China.
Vaccine
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China. Electronic address:
(1) Background: The administration of a live attenuated influenza vaccine (LAIV) has emerged as a viable option for preventing pediatric infections. The LAIV vaccine is available in China based on efficacy results. However, LAIV immunogenicity in children aged 3-17 years old in China has not yet to be studied and reported broadly.
View Article and Find Full Text PDFLinking multiple serological assays to infer dengue virus infections from paired samples using mixture models.
medRxiv
December 2024
Department of Medicine, University of California, San Francisco, USA.
Dengue virus (DENV) is an increasingly important human pathogen, with already half of the globe's population living in environments with transmission potential. Since only a minority of cases are captured by direct detection methods (RT-PCR or antigen tests), serological assays play an important role in the diagnostic process. However, individual assays can suffer from low sensitivity and specificity and interpreting results from multiple assays remains challenging, particularly because interpretations from multiple assays may differ, creating uncertainty over how to generate finalized interpretations.
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